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Cellosaurus A6/C1 (CVCL_B7ED)

[Text version]
Cell line name A6/C1
Synonyms A6-C1; A6C1
Accession CVCL_B7ED
Resource Identification Initiative To cite this cell line use: A6/C1 (RRID:CVCL_B7ED)
Comments Group: Amphibian cell line.
Characteristics: Selected for its high transepithelial resistance and for its responsiveness to aldosterone and antidiuretic hormone (PubMed=8392584).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Xenopus laevis (African clawed frog) (NCBI Taxonomy: 8355)
Hierarchy Parent: CVCL_F714 (A6-2F3)
Sex of cell Male
Age at sampling Adult stage
Category Spontaneously immortalized cell line

PubMed=3032984; DOI=10.1083/jcb.104.5.1231
Verrey F., Schaerer E., Zoerkler P., Paccolat M.-P., Geering K., Kraehenbuhl J.-P., Rossier B.C.
Regulation by aldosterone of Na+,K+-ATPase mRNAs, protein synthesis, and sodium transport in cultured kidney cells.
J. Cell Biol. 104:1231-1237(1987)

PubMed=8392584; DOI=10.1007/BF00232021
Verrey F., Digicaylioglu M., Bolliger U.
Polarized membrane movements in A6 kidney cells are regulated by aldosterone and vasopressin/vasotocin.
J. Membr. Biol. 133:213-226(1993)

PubMed=8189433; DOI=10.1007/BF00211070
Verrey F.
Antidiuretic hormone action in A6 cells: effect on apical Cl and Na conductances and synergism with aldosterone for NaCl reabsorption.
J. Membr. Biol. 138:65-76(1994)

Encyclopedic resources Wikidata; Q112927067
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number4