ID   A6/C1
AC   CVCL_B7ED
SY   A6-C1; A6C1
DR   Wikidata; Q112927067
RX   PubMed=3032984;
RX   PubMed=8189433;
RX   PubMed=8392584;
CC   Group: Amphibian cell line.
CC   Characteristics: Selected for its high transepithelial resistance and for its responsiveness to aldosterone and antidiuretic hormone (PubMed=8392584).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=8355; ! Xenopus laevis (African clawed frog)
HI   CVCL_F714 ! A6-2F3
SX   Male
AG   Adult stage
CA   Spontaneously immortalized cell line
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 5
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RX   PubMed=3032984; DOI=10.1083/jcb.104.5.1231;
RA   Verrey F., Schaerer E., Zoerkler P., Paccolat M.-P., Geering K.,
RA   Kraehenbuhl J.-P., Rossier B.C.;
RT   "Regulation by aldosterone of Na+,K+-ATPase mRNAs, protein synthesis,
RT   and sodium transport in cultured kidney cells.";
RL   J. Cell Biol. 104:1231-1237(1987).
//
RX   PubMed=8189433; DOI=10.1007/BF00211070;
RA   Verrey F.;
RT   "Antidiuretic hormone action in A6 cells: effect on apical Cl and Na
RT   conductances and synergism with aldosterone for NaCl reabsorption.";
RL   J. Membr. Biol. 138:65-76(1994).
//
RX   PubMed=8392584; DOI=10.1007/BF00232021;
RA   Verrey F., Digicaylioglu M., Bolliger U.;
RT   "Polarized membrane movements in A6 kidney cells are regulated by
RT   aldosterone and vasopressin/vasotocin.";
RL   J. Membr. Biol. 133:213-226(1993).
//