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Cellosaurus HCD-57 SHP2-D61Y (CVCL_B6YD)

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Cell line name HCD-57 SHP2-D61Y
Synonyms HCD57-SHP2-D61Y
Accession CVCL_B6YD
Resource Identification Initiative To cite this cell line use: HCD-57 SHP2-D61Y (RRID:CVCL_B6YD)
Comments Characteristics: EPO independent (DOI=10.1182/blood-2021-150007).
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9644; PTPN11 (Note=With p.Asp61Tyr).
Transformant: NCBI_TaxID; 11795; Friend murine leukemia virus (FrMLV).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Disease Mouse erythroid leukemia (NCIt: C21895)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_5289 (HCD-57)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

DOI=10.1182/blood-2021-150007
Yu-Ming Zhao, Yao Guo, Chun-Xiao He, Deng-Yang Zhang, Han-Zhong Pei, Ming Yang, Zhi-Guang Chang, Liu-Ting Yu, Jun-Bin Huang, Hong-Man Xue, Chen Chen ...Show all 13 authors... , Zhi-Zhuang Joe Zhao, Yun Chen; Show fewer authors
Establishment of stable cell lines representing juvenile myelomonocytic leukemia with SHP2 mutations.
Blood 138 Suppl. 1:4353-4353(2021)

Cross-references
Encyclopedic resources Wikidata; Q111733335
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number8