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Cellosaurus HCD-57 (CVCL_5289)

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Cell line name HCD-57
Synonyms HCD 57; HCD57; HC-D57
Accession CVCL_5289
Resource Identification Initiative To cite this cell line use: HCD-57 (RRID:CVCL_5289)
Comments Characteristics: EPO dependent.
Doubling time: ~24 hours (PubMed=1705834).
Transformant: NCBI_TaxID; 11795; Friend murine leukemia virus (FrMLV).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Disease Mouse erythroid leukemia (NCIt: C21895)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Children:
CVCL_B6YD (HCD-57 SHP2-D61Y)CVCL_B6YE (HCD-57 SHP2-E76K)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=HCD57
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-544.html
Publications

CLPUB00343
W. David Hankins, Kyung L. Chin, Robert Dons, J. Szabo;
Isolation of erythropoietin-independent cell lines suggests viability role for developmental hormones.
Blood 70 Suppl. 1:173a.547-173a.547(1987)

PubMed=2154592; DOI=10.1128/JVI.64.3.1057-1062.1990; PMCID=PMC249217
Sandra K. Ruscetti, Nancy J. Janesch, Anuradha Chakraborti, Stephen T. Sawyer, W. David Hankins;
Friend spleen focus-forming virus induces factor independence in an erythropoietin-dependent erythroleukemia cell line.
J. Virol. 64:1057-1062(1990)

PubMed=1705834; DOI=10.1182/blood.V77.6.1228.1228
Jerry Lepow Spivak, Thanh Pham, Maryann Isaacs, W. David Hankins;
Erythropoietin is both a mitogen and a survival factor.
Blood 77:1228-1233(1991)

DOI=10.1182/blood-2021-150007
Yu-Ming Zhao, Yao Guo, Chun-Xiao He, Deng-Yang Zhang, Han-Zhong Pei, Ming Yang, Zhi-Guang Chang, Liu-Ting Yu, Jun-Bin Huang, Hong-Man Xue, Chen Chen ...Show all 13 authors... , Zhi-Zhuang Joe Zhao, Yun Chen; Show fewer authors
Establishment of stable cell lines representing juvenile myelomonocytic leukemia with SHP2 mutations.
Blood 138 Suppl. 1:4353-4353(2021)

Cross-references
Cell line databases/resources TOKU-E; 3596
Encyclopedic resources Wikidata; Q54881841
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number17