Cellosaurus mDPCET (CVCL_B6Y9)
| Cell line name | mDPCET |
|---|---|
| Accession | CVCL_B6Y9 |
| Resource Identification Initiative | To cite this cell line use: mDPCET (RRID:CVCL_B6Y9) |
| Comments | Characteristics: Reversibly immortalized; exposure to tamoxifen induces the expression of the Cre gene that effects Cre/LoxP recombination and excise the SV40 TAG gene (PubMed=23299318). Characteristics: Transduced with a pHLox-CMV-TAg-IRES-TK lentiviral construct as well as a pCAG-ERT2iCreERT2-neo construct (PubMed=23299318). Genetic integration: Method=Transduction; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2). Genetic integration: Method=Transduction; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2). Genetic integration: Method=Transduction; Gene=UniProtKB; P06956; Escherichia phage P1 cre. Genetic integration: Method=Transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Embryonic tooth bud, dental papilla, molar; UBERON=UBERON_0015844. Cell type: Mesenchymal cell; CL=CL_0008019. |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: CD-1. |
| Hierarchy | Parent: CVCL_B6Y8 (mDPC6T) |
| Sex of cell | Sex unspecified |
| Age at sampling | 18-19FD |
| Category | Transformed cell line |
| Publications | PubMed=23299318; DOI=10.1007/s11626-012-9576-y |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112129239 |
| Entry history | |
| Entry creation | 17-Mar-2022 |
| Last entry update | 10-Apr-2025 |
| Version number | 6 |