ID   mDPCET
AC   CVCL_B6Y9
DR   Wikidata; Q112129239
RX   PubMed=23299318;
CC   Characteristics: Reversibly immortalized; exposure to tamoxifen induces the expression of the Cre gene that effects Cre/LoxP recombination and excise the SV40 TAG gene (PubMed=23299318).
CC   Characteristics: Transduced with a pHLox-CMV-TAg-IRES-TK lentiviral construct as well as a pCAG-ERT2iCreERT2-neo construct (PubMed=23299318).
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P06956; Escherichia phage P1 cre.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryonic tooth bud, dental papilla, molar; UBERON=UBERON_0015844.
CC   Cell type: Mesenchymal cell; CL=CL_0008019.
CC   Breed/subspecies: CD-1.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_B6Y8 ! mDPC6T
SX   Sex unspecified
AG   18-19FD
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 10-04-25; Version: 6
//
RX   PubMed=23299318; DOI=10.1007/s11626-012-9576-y;
RA   Lin H., Liu H., Sun Q., Yuan G.-H., Zhang L., Chen Z.;
RT   "Establishment and characterization of a tamoxifen-mediated reversible
RT   immortalized mouse dental papilla cell line.";
RL   In Vitro Cell. Dev. Biol. Anim. 49:114-121(2013).
//