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Cellosaurus SK-BR-3/nab-P (CVCL_B6Y6)

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Cell line name SK-BR-3/nab-P
Synonyms SK-BR-3/nab-Paclitaxel resistant
Accession CVCL_B6Y6
Resource Identification Initiative To cite this cell line use: SK-BR-3/nab-P (RRID:CVCL_B6Y6)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1748; CDH1; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0033 (SK-BR-3)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

DOI=10.4314/tjpr.v20i12.6
Chun-Yu Tian, Meng-Ze Xu, Hong-Xu Zhang, Han-Cheng Liu, Xing-Hua Liu, Li-Hui Ma;
LINC00173 mediates albumin paclitaxel resistance in breast cancer cells by regulating beta-catenin expression.
Trop. J. Pharm. Res. 20:2497-2503(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6Y6
Encyclopedic resources Wikidata; Q112041715
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number6