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Cellosaurus BJAB-B95.8.6 (CVCL_B6UM)

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Cell line name BJAB-B95.8.6
Accession CVCL_B6UM
Resource Identification Initiative To cite this cell line use: BJAB-B95.8.6 (RRID:CVCL_B6UM)
Comments Population: African; Kenyan.
Virology: EBV-negative cell line infected with EBV strain B95-8.
Karyotypic information: 45,XX,-8,3q+,7p+,8q+,10p+,11p+,inv(13) (PubMed=2995242).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Children:
CVCL_B6UN (BM1.5)CVCL_B6UX (BM10.1)CVCL_B6UY (BM11.1)
CVCL_B6UZ (BM12.1)CVCL_B6V0 (BM13.1)CVCL_B6V1 (BM14.1)
CVCL_B6V2 (BM15.3)CVCL_B6V3 (BM19)CVCL_B6UP (BM2.2)
CVCL_B6UQ (BM3.1)CVCL_B6UR (BM4.1)CVCL_B6US (BM5.2)
CVCL_B6UT (BM6.3)CVCL_B6UU (BM7.4)CVCL_B6UV (BM8.5)
CVCL_B6UW (BM9.1)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=2995242; DOI=10.1016/S0171-2985(85)80001-2
Andreas Ziegler, Claudia Muller, Jutta Heinig, Susan F. Radka, Jost Kompf, Christa Fonatsch;
Monosomy 6 in a human lymphoma line induced by selection with a monoclonal antibody.
Immunobiology 169:455-460(1985)

PubMed=3872842; DOI=10.1007/BF00375380
Barbel Spring, Christa Fonatsch, Claudia Muller, Graham Pawelec, Jost Kompf, Peter Wernet, Andreas Ziegler;
Refinement of HLA gene mapping with induced B-cell line mutants.
Immunogenetics 21:277-291(1985)

PubMed=8449221; DOI=10.1002/eji.1830230325
Barbara Uchanska-Ziegler, Elfriede Noessner, Andrea Schenk, Andreas Ziegler, Dolores Jean Schendel;
Soluble T cell receptor-like properties of an HLA-B35-specific monoclonal antibody (TU165).
Eur. J. Immunol. 23:734-738(1993)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6UM
Encyclopedic resources Wikidata; Q111732959
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number8