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Cellosaurus II-WA-Ramos (CVCL_B6UL)

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Cell line name II-WA-Ramos
Synonyms II WA-Ramos; II-WA-Ra #1
Accession CVCL_B6UL
Resource Identification Initiative To cite this cell line use: II-WA-Ramos (RRID:CVCL_B6UL)
Comments Population: Caucasian.
Virology: EBV-negative cell line infected with EBV from P3HR-1 cell line (Cellosaurus=CVCL_2676).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile254Asp (c.760_761AT>GA); Zygosity=Homozygous (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0597 (Ramos)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Publications

PubMed=181343; DOI=10.1159/000149930
George Klein, Beppino Carlo Giovanella, Anita Westman, John Sebastian Stehlin Jr., David Meday Mumford;
An EBV-genome-negative cell line established from an American Burkitt lymphoma; receptor characteristics. EBV infectibility and permanent conversion into EBV-positive sublines by in vitro infection.
Intervirology 5:319-334(1975)

PubMed=62724; DOI=10.1002/ijc.2910180513
George Klein, Jesper Zeuthen, Paul Ichiro Terasaki, Ronald James Billing, Ron Honig, Mikael Jondal, Anita Westman, Geoffrey Baverstock Clements;
Inducibility of the Epstein-Barr virus (EBV) cycle and surface marker properties of EBV-negative lymphoma lines and their in vitro EBV-converted sublines.
Int. J. Cancer 18:639-652(1976)

Cross-references
Encyclopedic resources Wikidata; Q111733490
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7