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Cellosaurus Mel Me (CVCL_B6KH)

[Text version]
Cell line name Mel Me
Synonyms mel Me
Accession CVCL_B6KH
Resource Identification Initiative To cite this cell line use: Mel Me (RRID:CVCL_B6KH)
Comments Group: Patented cell line.
Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 712D.
Derived from site: Metastatic; Back, skin; UBERON=UBERON_0001068.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=30551515).
HLA typing Source: Patent=RU2402603
Class I
HLA-AA*02,31
HLA-BB*56,58
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=16107020
Mikhailova I.N., Lukashina M.I., Baryshnikov A.Y., Morozova L.F., Burova O.S., Palkina T.N., Kozlov A.M., Golubeva V.A., Cheremushkin E.A., Doroshenko M.B., Demidov L.V., Kiselev S.L., Larin S.S., Georgiev G.P.
Melanoma cell lines as the basis for antitumor vaccine preparation.
Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005)

Patent=RU2402603
Mikhailova I.N., Baryshnikov A.Y., Demidov L.V., Kiselev S.L., Burova O.S., Morozova L.F., Baryshnikov K.A.
Cell line of human melanoma mel Me, applied for obtaining antitumour vaccine.
Patent number RU2402603, 27-Oct-2010

CLPUB00680
Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Burova O.S., Shubina I.Z., Kovalevsky D.A., Voronina E.S., Treshalina H.M., Lushnikova A.A., Tsyganova I.V., Mazurenko N.N.
Human skin melanoma cell lines collection.
(In) Management of malignant melanoma; pp.1-6; SM Group; Dover (2016)

PubMed=27313776; DOI=10.3892/ol.2016.4523
Vartanian A.A., Karshieva S., Dombrovsky V., Belyavsky A.
Melanoma educates mesenchymal stromal cells towards vasculogenic mimicry.
Oncol. Lett. 11:4264-4268(2016)

PubMed=30551515; DOI=10.1016/j.biopha.2018.11.109
Ryabaya O., Prokofieva A., Akasov R., Khochenkov D., Emelyanova M., Burov S., Markvicheva E., Inshakov A., Stepanova E.V.
Metformin increases antitumor activity of MEK inhibitor binimetinib in 2D and 3D models of human metastatic melanoma cells.
Biomed. Pharmacother. 109:2548-2560(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6KH
Encyclopedic resources Wikidata; Q112129282
Entry history
Entry creation17-Mar-2022
Last entry update05-Oct-2023
Version number5