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Cellosaurus Mel Me (CVCL_B6KH)

[Text version]
Cell line name Mel Me
Synonyms mel Me
Accession CVCL_B6KH
Resource Identification Initiative To cite this cell line use: Mel Me (RRID:CVCL_B6KH)
Comments Group: Patented cell line.
Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 712D.
Derived from site: Metastatic; Back, skin; UBERON=UBERON_0001068.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=30551515).
HLA typing Source: Patent=RU2402603
Class I
HLA-AA*02,31
HLA-BB*56,58
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=16107020
Irina Nikolaevna Mikhailova, Marina Igorevna Lukashina, Anatoly Yurievich Baryshnikov, Lidia Fyodorovna Morozova, Olga Semyonovna Burova, Tatiana Nikolaevna Palkina, Alexey Mikhailovich Kozlov, Valentina A. Golubeva, Eugene A. Cheremushkin, Maria B. Doroshenko, Lev Vadimovich Demidov ...Show all 14 authors... , Sergey L'vovich Kiselev, Sergey Sergeevich Larin, Georgii Pavlovich Georgiev; Show fewer authors
Melanoma cell lines as the basis for antitumor vaccine preparation.
Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005)

Patent=RU2402603
Irina Nikolaevna Mikhailova, Anatoly Yurievich Baryshnikov, Lev Vadimovich Demidov, Sergey L'vovich Kiselev, Olga Semyonovna Burova, Lidia Fyodorovna Morozova, Kirill Anatolevich Baryshnikov;
Cell line of human melanoma mel Me, applied for obtaining antitumour vaccine.
Patent number RU2402603, 27-Oct-2010

CLPUB00680
Irina Nikolaevna Mikhailova, Anatoly Yurievich Baryshnikov, Lidia Fyodorovna Morozova, Olga Semyonovna Burova, Irina Zhanovna Shubina, Dmitry A. Kovalevsky, Ekaterina Sergeevna Voronina, Helena Mikhailovna Treshalina, Anna A. Lushnikova, Irina V. Tsyganova, Natalia N. Mazurenko;
Human skin melanoma cell lines collection.
(In book chapter) Management of malignant melanoma; No_last_name, No_first_name (eds.); pp.6.1-6.6; SM Group; Dover; USA (2016)

PubMed=27313776; DOI=10.3892/ol.2016.4523; PMCID=PMC4888129
Amalia Artashevna Vartanian, Saida Karshieva, Vladislav Dombrovsky, Alexander Belyavsky;
Melanoma educates mesenchymal stromal cells towards vasculogenic mimicry.
Oncol. Lett. 11:4264-4268(2016)

PubMed=30551515; DOI=10.1016/j.biopha.2018.11.109
Oxana Ryabaya, Anastasia Prokofieva, Roman Akasov, Dmitry Khochenkov, Marina Emelyanova, Sergey Burov, Elena Markvicheva, Andrey N. Inshakov, Evgenia Vladislavovna Stepanova;
Metformin increases antitumor activity of MEK inhibitor binimetinib in 2D and 3D models of human metastatic melanoma cells.
Biomed. Pharmacother. 109:2548-2560(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6KH
Encyclopedic resources Wikidata; Q112129282
Entry history
Entry creation17-Mar-2022
Last entry update14-Aug-2025
Version number7