ID   Mel Me
AC   CVCL_B6KH
SY   mel Me
DR   cancercelllines; CVCL_B6KH
DR   Wikidata; Q112129282
RX   CelloPub=CLPUB00680;
RX   Patent=RU2402603;
RX   PubMed=16107020;
RX   PubMed=27313776;
RX   PubMed=30551515;
CC   Group: Patented cell line.
CC   Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 712D.
CC   HLA typing: A*02,31; B*56,58 (Patent=RU2402603).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=30551515).
CC   Derived from site: Metastatic; Back, skin; UBERON=UBERON_0001068.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 05-10-23; Version: 5
//
RX   CelloPub=CLPUB00680;
RA   Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Burova O.S.,
RA   Shubina I.Z., Kovalevsky D.A., Voronina E.S., Treshalina H.M.,
RA   Lushnikova A.A., Tsyganova I.V., Mazurenko N.N.;
RT   "Human skin melanoma cell lines collection.";
RL   (In) Management of malignant melanoma; pp.1-6; SM Group; Dover (2016).
//
RX   Patent=RU2402603;
RA   Mikhailova I.N., Baryshnikov A.Y., Demidov L.V., Kiselev S.L.,
RA   Burova O.S., Morozova L.F., Baryshnikov K.A.;
RT   "Cell line of human melanoma mel Me, applied for obtaining
RT   antitumour vaccine.";
RL   Patent number RU2402603, 27-Oct-2010.
//
RX   PubMed=16107020;
RA   Mikhailova I.N., Lukashina M.I., Baryshnikov A.Y., Morozova L.F.,
RA   Burova O.S., Palkina T.N., Kozlov A.M., Golubeva V.A.,
RA   Cheremushkin E.A., Doroshenko M.B., Demidov L.V., Kiselev S.L.,
RA   Larin S.S., Georgiev G.P.;
RT   "Melanoma cell lines as the basis for antitumor vaccine preparation.";
RL   Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005).
//
RX   PubMed=27313776; DOI=10.3892/ol.2016.4523;
RA   Vartanian A.A., Karshieva S., Dombrovsky V., Belyavsky A.;
RT   "Melanoma educates mesenchymal stromal cells towards vasculogenic
RT   mimicry.";
RL   Oncol. Lett. 11:4264-4268(2016).
//
RX   PubMed=30551515; DOI=10.1016/j.biopha.2018.11.109;
RA   Ryabaya O., Prokofieva A., Akasov R., Khochenkov D., Emelyanova M.,
RA   Burov S., Markvicheva E., Inshakov A., Stepanova E.V.;
RT   "Metformin increases antitumor activity of MEK inhibitor binimetinib
RT   in 2D and 3D models of human metastatic melanoma cells.";
RL   Biomed. Pharmacother. 109:2548-2560(2019).
//