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Cellosaurus F6D2 (CVCL_B6FG)

[Text version]
Cell line name F6D2
Accession CVCL_B6FG
Resource Identification Initiative To cite this cell line use: F6D2 (RRID:CVCL_B6FG)
Comments Population: African American.
Characteristics: The expression of the beta-galactosidase gene (lacZ) is under the control of a hypoxia-inducible EPO promoter (PubMed=22358881).
Doubling time: 45 hours (PubMed=22358881).
Transfected with: UniProtKB; P00722; Escherichia coli lacZ.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 903; AXIN1; Simple; p.Arg146Ter (c.436C>T); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
Disease Childhood hepatocellular carcinoma (NCIt: C7955)
Pediatric hepatocellular carcinoma (ORDO: Orphanet_33402)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0326 (Hep 3B2.1-7)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line

PubMed=22358881; DOI=10.1023/A:1007911816292
Shirai Y., Inagaki M., Yamaguchi M., Kambe T., Nagao M., Masuda S., Sasaki R.
Effect of hypoxia duration on the oxygen-dependent production of a recombinant protein, beta-galactosidase, by an animal cell line, F6D2, with a hypoxia-inducible enhancer.
Cytotechnology 25:71-77(1997)

Encyclopedic resources Wikidata; Q111733210
Entry history
Entry creation17-Mar-2022
Last entry update29-Jun-2023
Version number4