ID   F6D2
DR   Wikidata; Q111733210
RX   PubMed=22358881;
CC   Population: African American.
CC   Characteristics: The expression of the beta-galactosidase gene (lacZ) is under the control of a hypoxia-inducible EPO promoter (PubMed=22358881).
CC   Doubling time: 45 hours (PubMed=22358881).
CC   Sequence variation: Mutation; HGNC; 903; AXIN1; Simple; p.Arg146Ter (c.436C>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P00722; Escherichia coli lacZ.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7955; Childhood hepatocellular carcinoma
DI   ORDO; Orphanet_33402; Pediatric hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0326 ! Hep 3B2.1-7
SX   Male
AG   8Y
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 29-06-23; Version: 4
RX   PubMed=22358881; DOI=10.1023/A:1007911816292;
RA   Shirai Y., Inagaki M., Yamaguchi M., Kambe T., Nagao M., Masuda S.,
RA   Sasaki R.;
RT   "Effect of hypoxia duration on the oxygen-dependent production of a
RT   recombinant protein, beta-galactosidase, by an animal cell line, F6D2,
RT   with a hypoxia-inducible enhancer.";
RL   Cytotechnology 25:71-77(1997).