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Cellosaurus CHAHESe001-A-1 (CVCL_B5RQ)

[Text version]
Cell line name CHAHESe001-A-1
Synonyms CHA-hES NT6 B2M KO#67; KUSCRBe002-A-1
Accession CVCL_B5RQ
Resource Identification Initiative To cite this cell line use: CHAHESe001-A-1 (RRID:CVCL_B5RQ)
Comments From: Konkuk University; Seoul; South Korea.
Characteristics: The parent cell line was produced by somatic cell nuclear transfer from a dermal fibroblast (hDF) cells donated from a 59-year-old male patient with age-related macular degeneration.
Knockout cell: Method=CRISPR/Cas9; HGNC; 914; B2M.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Age-related macular degeneration (NCIt: C84391)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B5RM (CHA-NTK6)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell

PubMed=34971932; DOI=10.1016/j.scr.2021.102643
Lee O.-H., Lee S., Park M., Moon S., Hwang S., Kim B., Kim C.-Y., Lee D.R., Shim S.H., Park K.-H., Chung H.M., Choi Y.
Generation of a B2M homozygous knockout human somatic cell nuclear transfer-derived embryonic stem cell line using the CRISPR/Cas9 system.
Stem Cell Res. 59:102643-102643(2022)

Cell line databases/resources hPSCreg; CHAHESe001-A-1
Biological sample resources BioSamples; SAMEA11285969
Encyclopedic resources Wikidata; Q111733119
Entry history
Entry creation17-Mar-2022
Last entry update29-Jun-2023
Version number5