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Cellosaurus CHA-NTK6 (CVCL_B5RM)

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Cell line name CHA-NTK6
Synonyms NTK-ESC #6; NT assisted by KDM4A-ESC #6; CHA-NT #6; CHA-hES NT6; CHAHESe001-A
Accession CVCL_B5RM
Resource Identification Initiative To cite this cell line use: CHA-NTK6 (RRID:CVCL_B5RM)
Comments From: CHA University; Seongnam; South Korea.
Characteristics: Produced by somatic cell nuclear transfer from a dermal fibroblast (hDF) cells donated from a 52-year-old female patient with age-related macular degeneration.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Disease Age-related macular degeneration (NCIt: C84391)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B5RQ (CHAHESe001-A-1)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=26526725

Markers:
AmelogeninX
CSF1PO10,13
D2S133817,24
D3S135815,16
D5S81810,11
D7S82011,12
D8S117912,13
D13S3178,11
D16S53911,13
D18S5114,15
D19S43313,14.2
D21S1129
FGA23
TH019
TPOX8
vWA14,17

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Publications

PubMed=26526725; DOI=10.1016/j.stem.2015.10.001
Young-Gie Chung, Shogo Matoba, Yu-Ting Liu, Jin Hee Eum, Fa-Long Lu, Wei Jiang, Jeoung Eun Lee, Vicken Sepilian, Kwang Yul Cha, Dong Ryul Lee, Yi Zhang;
Histone demethylase expression enhances human somatic cell nuclear transfer efficiency and promotes derivation of pluripotent stem cells.
Cell Stem Cell 17:758-766(2015)

PubMed=34971932; DOI=10.1016/j.scr.2021.102643
Ok-Hee Lee, Siyoung Lee, Miseon Park, Sohyeon Moon, Semi Hwang, Byeongseok Kim, C-Yoon Kim, Dong Ryul Lee, Sung Han Shim, Keun-Hong Park, Hyung-Min Chung, Youngsok Choi;
Generation of a B2M homozygous knockout human somatic cell nuclear transfer-derived embryonic stem cell line using the CRISPR/Cas9 system.
Stem Cell Res. 59:102643-102643(2022)

Cross-references
Cell line databases/resources hPSCreg; CHAHESe001-A
Biological sample resources BioSamples; SAMEA11039557
Encyclopedic resources Wikidata; Q111733112
Gene expression databases GEO; GSM1891813
GEO; GSM1891814
Entry history
Entry creation17-Mar-2022
Last entry update10-Apr-2025
Version number5