Cellosaurus cell line IMEDEAi001-F-1 (CVCL

Cellosaurus IMEDEAi001-F-1 (CVCL_B5LL)

Cross-references
Cell line name	IMEDEAi001-F-1
Accession	CVCL_B5LL
Resource Identification Initiative	To cite this cell line use: IMEDEAi001-F-1 (RRID:CVCL_B5LL)
Comments	From: Instituto Mediterraneo de Estudios Avanzados; Esporles; Spain. Population: Caucasian. Omics: Variations; Array-based CGH. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple_corrected; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous; Note=By TALEN (PubMed=32373648).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_VD78 (IMEDEAi001-F)
Sex of cell	Female
Age at sampling	8Y
Category	Induced pluripotent stem cell
Publications	PubMed=32373648; DOI=10.1016/j.omtm.2020.04.005; PMCID=PMC7195499 Aarne Fleischer, Sara Vallejo-Diez, Jose Maria Martin-Fernandez, Almudena Sanchez-Gilabert, Monica Castresana, Angel del Pozo, Amaia Esquisabel, Silvia Avila, Jose Luis Castrillo, Eusebio Gainza, Jose Luis Pedraz ...Show all 13 authors... , Miguel Vinas, Daniel Bachiller; Show fewer authors iPSC-derived intestinal organoids from cystic fibrosis patients acquire CFTR activity upon TALEN-mediated repair of the p.F508del mutation. Mol. Ther. Methods Clin. Dev. 17:858-870(2020)
Cell line databases/resources	hPSCreg; IMEDEAi001-F-1
Encyclopedic resources	Wikidata; Q111733512
Entry history
Entry creation	17-Mar-2022
Last entry update	10-Apr-2025
Version number	6