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Cellosaurus OCUT-1F (CVCL_B5GF)

[Text version]
Cell line name OCUT-1F
Synonyms Osaka City University Thyroid-1F
Accession CVCL_B5GF
Resource Identification Initiative To cite this cell line use: OCUT-1F (RRID:CVCL_B5GF)
Comments Population: Japanese.
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=24357248).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Homozygous; Note=In promoter (from parent cell line).
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6017 (OCUT-1)
Sex of cell Female
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1897

Markers:
AmelogeninX
CSF1PO12,13
D5S8189,13
D7S82011,13
D13S3178
D16S53910,12
TH016,9
TPOX8,11
vWA16,18

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Publications

PubMed=24357248; DOI=10.1007/s00268-013-2409-7
Onoda N., Nakamura M., Aomatsu N., Noda S., Kashiwagi S., Hirakawa K.
Establishment, characterization and comparison of seven authentic anaplastic thyroid cancer cell lines retaining clinical features of the original tumors.
World J. Surg. 38:688-695(2014)

PubMed=26137260; DOI=10.3892/mco.2015.496
Onoda N., Nakamura M., Aomatsu N., Noda S., Kashiwagi S., Kurata K., Uchino S., Hirakawa K.
Significant cytostatic effect of everolimus on a gefitinib-resistant anaplastic thyroid cancer cell line harboring PI3KCA gene mutation.
Mol. Clin. Oncol. 3:522-526(2015)

Cross-references
Cell line collections (Providers) JCRB; JCRB1897
Cell line databases/resources cancercelllines; CVCL_B5GF
Encyclopedic resources Wikidata; Q110433123
Entry history
Entry creation16-Dec-2021
Last entry update02-May-2024
Version number6