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Cellosaurus TL-Om1 (CVCL_B473)

[Text version]
Cell line name TL-Om1
Synonyms TL-om1; TL-OM1; TLom1; TLOM1; TL-OML
Accession CVCL_B473
Resource Identification Initiative To cite this cell line use: TL-Om1 (RRID:CVCL_B473)
Comments Population: Japanese.
Biotechnology: Used as a reference cell line to standardize the qPCR of HTLV-1 (PubMed=25502533; PubMed=30125970).
Characteristics: IL2 dependent.
Virology: The HTLV-1 provirus is monoclonally integrated in chromosome 1 (PubMed=25502533).
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Disease Adult T-cell leukemia/lymphoma (NCIt: C3184)
Adult T-cell leukemia/lymphoma (ORDO: Orphanet_86875)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=6088403; DOI=10.1002/ijc.2910340213
Kazuo Sugamura, Masahiro Fujii, Mari Kannagi, Mitsuru Sakitani, Masao Takeuchi, Yorio Hinuma;
Cell surface phenotypes and expression of viral antigens of various human cell lines carrying human T-cell leukemia virus.
Int. J. Cancer 34:221-228(1984)

PubMed=2981920; DOI=10.4049/jimmunol.134.3.1728
Kazuo Shimizu, Toshio Hirano, Kazuaki Ishibashi, Naoko Nakano, Tetsuya Taga, Kazuo Sugamura, Yuichi Yamamura, Tadamitsu Kishimoto;
Immortalization of BGDF (BCGF II)- and BCDF-producing T cells by human T cell leukemia virus (HTLV) and characterization of human BGDF (BCGF II).
J. Immunol. 134:1728-1733(1985)

PubMed=7662981; DOI=10.1182/blood.V86.6.2350.bloodjournal8662350
Kazunori Imada, Akifumi Takaori-Kondo, Tsuyoshi Akagi, Kunitada Shimotohno, Kazuo Sugamura, Toshio Hattori, Hirohiko Yamabe, Minoru Okuma, Takashi Uchiyama;
Tumorigenicity of human T-cell leukemia virus type I-infected cell lines in severe combined immunodeficient mice and characterization of the cells proliferating in vivo.
Blood 86:2350-2357(1995)

PubMed=10706122
Kisato Nosaka, Michiyuki Maeda, Sadahiro Tamiya, Tatsunori Sakai, Hiroaki Mitsuya, Masao Matsuoka;
Increasing methylation of the CDKN2A gene is associated with the progression of adult T-cell leukemia.
Cancer Res. 60:1043-1048(2000)

PubMed=25502533; DOI=10.1128/jcm.02254-14; PMCID=PMC4298509
Madoka Kuramitsu, Kazu Okuma, Makoto Yamagishi, Tadanori Yamochi, Sanaz Firouzi, Haruka Momose, Takuo Mizukami, Kazuya Takizawa, Kumiko Araki, Kazuo Sugamura, Kazunari Yamaguchi ...Show all 13 authors... , Toshiki Watanabe, Isao Hamaguchi; Show fewer authors
Identification of TL-Om1, an adult T-cell leukemia (ATL) cell line, as reference material for quantitative PCR for human T-lymphotropic virus 1.
J. Clin. Microbiol. 53:587-596(2015)

PubMed=30125970; DOI=10.1111/1348-0421.12644
Madoka Kuramitsu, Kazu Okuma, Makoto Nakashima, Tomoo Sato, Daisuke Sasaki, Hiroo Hasegawa, Kazumi Umeki, Ryuji Kubota, Keiko Sasada, Rieko Sobata, Chieko Matsumoto ...Show all 30 authors... , Noriaki Kaneko, Kenta Tezuka, Sahoko Matsuoka, Atae Utsunomiya, Ki-Ryang Koh, Masao Ogata, Kenji Ishitsuka, Mai Taki, Kisato Nosaka, Kaoru Uchimaru, Masako Iwanaga, Yasuko Sagara, Yoshihisa Yamano, Akihiko Okayama, Kiyonori Miura, Masahiro Satake, Shigeru Saito, Toshiki Watanabe, Isao Hamaguchi; Show fewer authors
Development of reference material with assigned value for human T-cell leukemia virus type 1 quantitative PCR in Japan.
Microbiol. Immunol. 62:673-676(2018)

Cross-references
Cell line collections (Providers) RCB; RCB2086 - Discontinued
TKG; TKG 0289
Encyclopedic resources Wikidata; Q54972603
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number17