• Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=7753552; PubMed=15150091; PubMed=28745431).
  

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Use of a newly established human cell line (SU-CCS-1) to demonstrate the relationship of clear cell sarcoma to malignant melanoma.
Cancer Res. 44:1265-1274(1984)

PubMed=7753552
Brown A.D., Lopez-Terrada D.H., Denny C.T., Lee K.A.W.
Promoters containing ATF-binding sites are de-regulated in cells that express the EWS/ATF1 oncogene.
Oncogene 10:1749-1756(1995)

PubMed=12966428; DOI=10.1038/sj.bjc.6601212; PMCID=PMC2376962
Li K.K.C., Goodall J., Goding C.R., Liao S.-K., Wang C.-H., Lin Y.-C., Hiraga H., Nojima T., Nagashima K., Schaefer K.-L., Lee K.A.W.
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma.
Br. J. Cancer 89:1072-1078(2003)

PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809
Schaefer K.-L., Brachwitz K., Wai D.H., Braun Y., Diallo R., Korsching E., Eisenacher M., Voss R., van Valen F., Baer C., Selle B., Spahn L., Liao S.-K., Lee K.A.W., Hogendoorn P.C.W., Reifenberger G., Gabbert H.E., Poremba C.
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.
Cancer Res. 64:3395-3405(2004)

PubMed=16766266; DOI=10.1016/j.ccr.2006.04.021
Davis I.J., Kim J.J., Ozsolak F., Widlund H.R., Rozenblatt-Rosen O., Granter S.R., Du J.-Y., Fletcher J.A., Denny C.T., Lessnick S.L., Linehan W.M., Kung A.L.-J., Fisher D.E.
Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.
Cancer Cell 9:473-484(2006)

PubMed=28745431; DOI=10.1002/cam4.1130; PMCID=PMC5603837
Nakai T., Imura Y., Tamiya H., Yamada S., Nakai S., Yasuda N., Kaneko K., Outani H., Takenaka S., Hamada K., Myoui A., Araki N., Ueda T., Itoh K., Yoshikawa H., Naka N.
Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma.
Cancer Med. 6:2121-2130(2017)

PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623
Rasmussen S.V., Wozniak A., Lathara M., Goldenberg J.M., Samudio B.M., Bickford L.R., Nagamori K., Wright H., Woods A.D., Chauhan S., Lee C.-J., Rudzinski E.R., Swift M.K., Kondo T., Fisher D.E., Imyanitov E.N., Machado I., Llombart-Bosch A., Andrulis I.L., Gokgoz N., Wunder J.S., Moritake H., Nakamura T., Srinivasa G., Thway K., Jones R.L., Huang P.H., Berlow N.E., Schoffski P., Keller C.
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma.
Br. J. Cancer 128:1941-1954(2023)