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Cellosaurus SU-CCS-1 (CVCL_B470)

[Text version]
Cell line name SU-CCS-1
Synonyms Su-ccs-1; Su CCS-1; SU-CCS1; SUCCS1
Accession CVCL_B470
Resource Identification Initiative To cite this cell line use: SU-CCS-1 (RRID:CVCL_B470)
Comments Population: Caucasian.
Doubling time: ~52 hours (PubMed=6362860).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 16Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2971; PubMed=36959380

Markers:
AmelogeninX
CSF1PO10,11
D2S133816,20
D3S135815,18
D5S81812,14
D7S82012
D8S117910
D13S3178
D16S53911
D18S5112,16
D19S43312,14
D21S1128,30
FGA22.2,24
Penta D9,12
Penta E12
TH016,7
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=6362860
Alan L. Epstein, Alice O. Martin, Richard Kempson;
Use of a newly established human cell line (SU-CCS-1) to demonstrate the relationship of clear cell sarcoma to malignant melanoma.
Cancer Res. 44:1265-1274(1984)

PubMed=7753552
Andrew D. Brown, Dolores H. Lopez-Terrada, Christopher T. Denny, Kevin A.W. Lee;
Promoters containing ATF-binding sites are de-regulated in cells that express the EWS/ATF1 oncogene.
Oncogene 10:1749-1756(1995)

PubMed=12966428; DOI=10.1038/sj.bjc.6601212; PMCID=PMC2376962
Kim K.C. Li, Jane Goodall, Colin Ronald Goding, Shuen-Kuei Liao, Cheng-Hsu Wang, Y.-C. Lin, Hiroaki Hiraga, Takayuki Nojima, Kazuo Nagashima, Karl-Ludwig Schaefer, Kevin A.W. Lee;
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma.
Br. J. Cancer 89:1072-1078(2003)

PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809
Karl-Ludwig Schaefer, Kristin Brachwitz, Daniel H. Wai, Yvonne Braun, Raihanatou Diallo, Eberhard Korsching, Martin Eisenacher, Reinhard Voss, Frans van Valen, Claudia Baer, Barbara Selle ...Show all 18 authors... , Laura Spahn, Shuen-Kuei Liao, Kevin A.W. Lee, Pancras Cornelis Wilhelmus Hogendoorn, Guido Reifenberger, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.
Cancer Res. 64:3395-3405(2004)

PubMed=16766266; DOI=10.1016/j.ccr.2006.04.021
Ian J. Davis, Jessica J. Kim, Fatih Ozsolak, Hans R. Widlund, Orit Rozenblatt-Rosen, Scott R. Granter, Jin-Yan Du, Jonathan A. Fletcher, Christopher T. Denny, Stephen Lee Lessnick, William Marston Linehan ...Show all 13 authors... , Andrew Li-Jen Kung, David Erich Fisher; Show fewer authors
Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.
Cancer Cell 9:473-484(2006)

PubMed=28745431; DOI=10.1002/cam4.1130; PMCID=PMC5603837
Takaaki Nakai, Yoshinori Imura, Hironari Tamiya, Shutaro Yamada, Sho Nakai, Naohiro Yasuda, Keiko Kaneko, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, Akira Myoui ...Show all 16 authors... , Nobuhito Araki, Takafumi Ueda, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka; Show fewer authors
Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma.
Cancer Med. 6:2121-2130(2017)

PubMed=36959380; DOI=10.1038/s41416-023-02222-0; PMCID=PMC10147623
Samuel V. Rasmussen, Agnieszka Wozniak, Melvin Lathara, Joshua M. Goldenberg, Benjamin Michael Samudio, Lissett Ramirez Bickford, Kiyo Nagamori, Hollis Wright, Andrew D. Woods, Shefali Chauhan, Che-Jui Lee ...Show all 30 authors... , Erin R. Rudzinski, Michael K. Swift, Tadashi Kondo, David Erich Fisher, Evgeny N. Imyanitov, Isidro Machado, Antonio Llombart-Bosch, Irene L. Andrulis, Nalan Gokgoz, Jay Steven Wunder, Hiroshi Moritake, Takuro Nakamura, Ganapati Srinivasa, Khin Thway, Robin L. Jones, Paul H. Huang, Noah E. Berlow, Patrick Schoffski, Charles Keller; Show fewer authors
Functional genomics of human clear cell sarcoma: genomic, transcriptomic and chemical biology landscape for clear cell sarcoma.
Br. J. Cancer 128:1941-1954(2023)

Cross-references
Cell line collections (Providers) ATCC; CRL-2971
Encyclopedic resources Wikidata; Q54970704
Polymorphism and mutation databases Cosmic; 1092866
Sequence databases EGA; EGAD00001008611
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18