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Cellosaurus OHS (CVCL_B450)

[Text version]
Cell line name OHS
Synonyms OHSX; OHS/X; OHS-50; OHS-50T
Accession CVCL_B450
Resource Identification Initiative To cite this cell line use: OHS (RRID:CVCL_B450)
Comments Population: Caucasian.
Doubling time: ~36 hours (PubMed=21519327).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone, distal femur; UBERON=UBERON_0004406.
Sequence variations
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_R724 (OHS-4)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): PubMed=19787792

Markers:
AmelogeninX
D2S133824,25
D3S135816,19
D5S81810
D8S117913
D16S53912
D18S5112,14
D19S43314,15
D21S1130
FGA20,22
SE3326.2
TH019
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=3459716; DOI=10.1002/ijc.2910380107
Oystein Fodstad, Anton Brogger, Oyvind Sverre Bruland, Oyvin P. Solheim, Jahn M. Nesland, Alexander Pihl;
Characteristics of a cell line established from a patient with multiple osteosarcoma, appearing 13 years after treatment for bilateral retinoblastoma.
Int. J. Cancer 38:33-40(1986)

PubMed=2233717; DOI=10.1128/mcb.10.11.5772-5781.1990; PMCID=PMC361354
Lisa Diller, Jayne Kassel, Camille E. Nelson, Magdalena A. Gryka, Gregory Litwak, Mark Gebhardt, Brigitte Bressac, Mehmet Ozturk, Suzanne J. Baker, Bert Vogelstein, Stephen H. Friend;
p53 functions as a cell cycle control protein in osteosarcomas.
Mol. Cell. Biol. 10:5772-5781(1990)

PubMed=8198963; DOI=10.1038/bjc.1994.200; PMCID=PMC1969443
Inge Kjonniksen, Phil D. Rye, Oystein Fodstad;
Helix pomatia agglutinin binding in human tumour cell lines: correlation with pulmonary metastases in nude mice.
Br. J. Cancer 69:1021-1024(1994)

PubMed=19787792; DOI=10.1002/gcc.20717
Laura Ottaviano, Karl-Ludwig Schaefer, Melanie Gajewski, Wolfgang Huckenbeck, Stefan E. Baldus, Uwe Rogel, Carlos Mackintosh, Enrique de Alava, Ola Myklebost, Stine Henrichson Kresse, Leonardo Andres Meza-Zepeda ...Show all 18 authors... , Massimo Serra, Anne-Marie Cleton-Jansen, Pancras Cornelis Wilhelmus Hogendoorn, Horst Buerger, Thomas Aigner, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=21519327; DOI=10.1038/labinvest.2011.72
Alexander B. Mohseny, Isidro Machado, Yong-Ping Cai, Karl-Ludwig Schaefer, Massimo Serra, Pancras Cornelis Wilhelmus Hogendoorn, Antonio Llombart-Bosch, Anne-Marie Cleton-Jansen;
Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.
Lab. Invest. 91:1195-1205(2011)

PubMed=23144859; DOI=10.1371/journal.pone.0048262; PMCID=PMC3492335
Stine Henrichson Kresse, Halfdan Rydbeck, Magne Skarn, Heidi Maria Namlos, Ana Heslanyeth Barragan-Polania, Anne-Marie Cleton-Jansen, Massimo Serra, Knut Liestol, Pancras Cornelis Wilhelmus Hogendoorn, Eivind Hovig, Ola Myklebost, Leonardo Andres Meza-Zepeda;
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.
PLoS ONE 7:e48262.1-e48262.20(2012)

PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476
Beverly A. Teicher, Eric C. Polley, Mark W. Kunkel, David Evans, Thomas E. Silvers, Rene M. Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, John Connelly ...Show all 14 authors... , Erik Harris, Anne Monks, Joel Morris; Show fewer authors
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B450
Encyclopedic resources Wikidata; Q38098672
Gene expression databases GEO; GSM879220
GEO; GSM1676308
GEO; GSM1701642
Polymorphism and mutation databases Cosmic; 1529909
IARC_TP53; 2149
Progenetix; CVCL_B450
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18