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Cellosaurus MHM (CVCL_B426)

[Text version]
Cell line name MHM
Synonyms MHMX
Accession CVCL_B426
Resource Identification Initiative To cite this cell line use: MHM (RRID:CVCL_B426)
Comments Doubling time: ~60 hours (PubMed=21519327).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Bone, pelvis; UBERON=UBERON_0012179.
Sequence variations
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): PubMed=19787792

Markers:
AmelogeninX
D2S133819,24
D3S135817,18
D5S81812,13
D8S117910,13
D16S5399,13
D18S5112,14
D19S43314,15
D21S1130.2,32
FGA19,23
SE3324.2
TH019.3
TPOX9,12
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=8198963; DOI=10.1038/bjc.1994.200; PMCID=PMC1969443
Inge Kjonniksen, Phil D. Rye, Oystein Fodstad;
Helix pomatia agglutinin binding in human tumour cell lines: correlation with pulmonary metastases in nude mice.
Br. J. Cancer 69:1021-1024(1994)

PubMed=17354236; DOI=10.1002/ijc.22643
Christoph R. Muller, Erik B. Paulsen, Paul Noordhuis, Florence Pedeutour, Gunnar Saeter, Ola Myklebost;
Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A.
Int. J. Cancer 121:199-205(2007)

PubMed=19787792; DOI=10.1002/gcc.20717
Laura Ottaviano, Karl-Ludwig Schaefer, Melanie Gajewski, Wolfgang Huckenbeck, Stefan E. Baldus, Uwe Rogel, Carlos Mackintosh, Enrique de Alava, Ola Myklebost, Stine Henrichson Kresse, Leonardo Andres Meza-Zepeda ...Show all 18 authors... , Massimo Serra, Anne-Marie Cleton-Jansen, Pancras Cornelis Wilhelmus Hogendoorn, Horst Buerger, Thomas Aigner, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Genes Chromosomes Cancer 49:40-51(2010)

PubMed=21519327; DOI=10.1038/labinvest.2011.72
Alexander B. Mohseny, Isidro Machado, Yong-Ping Cai, Karl-Ludwig Schaefer, Massimo Serra, Pancras Cornelis Wilhelmus Hogendoorn, Antonio Llombart-Bosch, Anne-Marie Cleton-Jansen;
Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.
Lab. Invest. 91:1195-1205(2011)

PubMed=23144859; DOI=10.1371/journal.pone.0048262; PMCID=PMC3492335
Stine Henrichson Kresse, Halfdan Rydbeck, Magne Skarn, Heidi Maria Namlos, Ana Heslanyeth Barragan-Polania, Anne-Marie Cleton-Jansen, Massimo Serra, Knut Liestol, Pancras Cornelis Wilhelmus Hogendoorn, Eivind Hovig, Ola Myklebost, Leonardo Andres Meza-Zepeda;
Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma.
PLoS ONE 7:e48262.1-e48262.20(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B426
Anatomy/cell type resources BTO; BTO_0006420
Encyclopedic resources Wikidata; Q54905565
Gene expression databases GEO; GSM879218
Polymorphism and mutation databases Cosmic; 1529904
IARC_TP53; 27031
Progenetix; CVCL_B426
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number18