ID   MHM
AC   CVCL_B426
SY   MHMX
DR   BTO; BTO_0006420
DR   cancercelllines; CVCL_B426
DR   Cosmic; 1529904
DR   GEO; GSM879218
DR   IARC_TP53; 27031
DR   Progenetix; CVCL_B426
DR   Wikidata; Q54905565
RX   PubMed=8198963;
RX   PubMed=17354236;
RX   PubMed=19787792;
RX   PubMed=21519327;
RX   PubMed=23144859;
CC   Doubling time: ~60 hours (PubMed=21519327).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=19787792).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=19787792).
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Bone, pelvis; UBERON=UBERON_0012179.
ST   Source(s): PubMed=19787792
ST   Amelogenin: X
ST   D16S539: 9,13
ST   D18S51: 12,14
ST   D19S433: 14,15
ST   D21S11: 30.2,32
ST   D2S1338: 19,24
ST   D3S1358: 17,18
ST   D5S818: 12,13
ST   D8S1179: 10,13
ST   FGA: 19,23
ST   SE33: 24.2
ST   TH01: 9.3
ST   TPOX: 9,12
ST   vWA: 17,18
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   41Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 18
//
RX   PubMed=8198963; DOI=10.1038/bjc.1994.200; PMCID=PMC1969443;
RA   Kjonniksen I., Rye P.D., Fodstad O.;
RT   "Helix pomatia agglutinin binding in human tumour cell lines:
RT   correlation with pulmonary metastases in nude mice.";
RL   Br. J. Cancer 69:1021-1024(1994).
//
RX   PubMed=17354236; DOI=10.1002/ijc.22643;
RA   Muller C.R., Paulsen E.B., Noordhuis P., Pedeutour F., Saeter G.,
RA   Myklebost O.;
RT   "Potential for treatment of liposarcomas with the MDM2 antagonist
RT   Nutlin-3A.";
RL   Int. J. Cancer 121:199-205(2007).
//
RX   PubMed=19787792; DOI=10.1002/gcc.20717;
RA   Ottaviano L., Schaefer K.-L., Gajewski M., Huckenbeck W., Baldus S.E.,
RA   Rogel U., Mackintosh C., de Alava E., Myklebost O., Kresse S.H.,
RA   Meza-Zepeda L.A., Serra M., Cleton-Jansen A.-M., Hogendoorn P.C.W.,
RA   Buerger H., Aigner T., Gabbert H.E., Poremba C.;
RT   "Molecular characterization of commonly used cell lines for bone tumor
RT   research: a trans-European EuroBoNet effort.";
RL   Genes Chromosomes Cancer 49:40-51(2010).
//
RX   PubMed=21519327; DOI=10.1038/labinvest.2011.72;
RA   Mohseny A.B., Machado I., Cai Y.-P., Schaefer K.-L., Serra M.,
RA   Hogendoorn P.C.W., Llombart-Bosch A., Cleton-Jansen A.-M.;
RT   "Functional characterization of osteosarcoma cell lines provides
RT   representative models to study the human disease.";
RL   Lab. Invest. 91:1195-1205(2011).
//
RX   PubMed=23144859; DOI=10.1371/journal.pone.0048262; PMCID=PMC3492335;
RA   Kresse S.H., Rydbeck H., Skarn M., Namlos H.M., Barragan-Polania A.H.,
RA   Cleton-Jansen A.-M., Serra M., Liestol K., Hogendoorn P.C.W., Hovig E.,
RA   Myklebost O., Meza-Zepeda L.A.;
RT   "Integrative analysis reveals relationships of genetic and epigenetic
RT   alterations in osteosarcoma.";
RL   PLoS ONE 7:e48262.1-e48262.20(2012).
//