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Cellosaurus HOK-16B (CVCL_B405)

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Cell line name HOK-16B
Synonyms HOK16B; Human Oral Keratinocytes-16B
Accession CVCL_B405
Resource Identification Initiative To cite this cell line use: HOK-16B (RRID:CVCL_B405)
Comments Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Oral cavity; UBERON=UBERON_0000167.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B406 (HOK-16B-BaP)CVCL_6G60 (HOK-16B-MSEE)
Originate from same individual CVCL_B404 ! HOK-16A
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO10,11
D5S8189,10
D7S82012
D13S3179,12
D16S53912
TH018,9
TPOX8,11
vWA17,19

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Publications

PubMed=1654226; DOI=10.1093/carcin/12.9.1627
No-Hee Park, Byung-Moo Min, Sheng-Lin Li, Min-Zhong Huang, Henry M. Cherick, Jay Doniger;
Immortalization of normal human oral keratinocytes with type 16 human papillomavirus.
Carcinogenesis 12:1627-1631(1991)

PubMed=1330348; DOI=10.1093/carcin/13.11.1981
Sheng-Lin Li, Myong Soo Kim, Henry M. Cherrick, Jay Doniger, No-Hee Park;
Sequential combined tumorigenic effect of HPV-16 and chemical carcinogens.
Carcinogenesis 13:1981-1987(1992)

PubMed=10675494; DOI=10.3892/ijo.16.3.591
Masayuki Itakura, Shunsuke Mori, No-Hee Park, Benjamin Bonavida;
Both HPV and carcinogen contribute to the development of resistance to apoptosis during oral carcinogenesis.
Int. J. Oncol. 16:591-597(2000)

PubMed=12907203; DOI=10.1016/S1368-8375(03)00049-6
Eric A. Swan, Samar A. Jasser, Floyd Christopher Holsinger, Dao Doan, Corazon D. Bucana, Jeffrey N. Myers;
Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer.
Oral Oncol. 39:648-655(2003)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Mei Zhao, Daisuke Sano, Curtis R. Pickering, Samar A. Jasser, Ying C. Henderson, Gary L. Clayman, Erich M. Sturgis, Thomas J. Ow, Reuben Lotan, Thomas E. Carey, Peter G. Sacks ...Show all 15 authors... , Jennifer Rubin Grandis, David Sidransky, Nils-Erik Heldin, Jeffrey N. Myers; Show fewer authors
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=32574978; DOI=10.1016/j.tranon.2020.100808; PMCID=PMC7317296
Thankam S. Nair, Trey B. Thomas, Lucy Yang, Bala Naveen Kakaraparthi, Anna C. Morris, Alanna M. Clark, Lora Perry Campredon, Andrew F. Brouwer, Marisa C. Eisenberg, Rafael Meza, Thomas E. Carey;
Characteristics of head and neck squamous cell carcinoma cell lines reflect human tumor biology independent of primary etiologies and HPV status.
Transl. Oncol. 13:100808.1-100808.9(2020)

Cross-references
Encyclopedic resources Wikidata; Q54890135
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number13