ID   HOK-16B
AC   CVCL_B405
SY   HOK16B; Human Oral Keratinocytes-16B
DR   Wikidata; Q54890135
RX   PubMed=1330348;
RX   PubMed=1654226;
RX   PubMed=10675494;
RX   PubMed=12907203;
RX   PubMed=21868764;
RX   PubMed=32574978;
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Oral cavity; UBERON=UBERON_0000167.
CC   Cell type: Keratinocyte; CL=CL_0000312.
ST   Source(s): PubMed=21868764
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 9,12
ST   D16S539: 12
ST   D5S818: 9,10
ST   D7S820: 12
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 17,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_B404 ! HOK-16A
SX   Male
AG   Age unspecified
CA   Transformed cell line
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 13
//
RX   PubMed=1330348; DOI=10.1093/carcin/13.11.1981;
RA   Li S.-L., Kim M.S., Cherrick H.M., Doniger J., Park N.-H.;
RT   "Sequential combined tumorigenic effect of HPV-16 and chemical
RT   carcinogens.";
RL   Carcinogenesis 13:1981-1987(1992).
//
RX   PubMed=1654226; DOI=10.1093/carcin/12.9.1627;
RA   Park N.-H., Min B.-M., Li S.-L., Huang M.-Z., Cherick H.M., Doniger J.;
RT   "Immortalization of normal human oral keratinocytes with type 16 human
RT   papillomavirus.";
RL   Carcinogenesis 12:1627-1631(1991).
//
RX   PubMed=10675494; DOI=10.3892/ijo.16.3.591;
RA   Itakura M., Mori S., Park N.-H., Bonavida B.;
RT   "Both HPV and carcinogen contribute to the development of resistance
RT   to apoptosis during oral carcinogenesis.";
RL   Int. J. Oncol. 16:591-597(2000).
//
RX   PubMed=12907203; DOI=10.1016/S1368-8375(03)00049-6;
RA   Swan E.A., Jasser S.A., Holsinger F.C., Doan D., Bucana C.D.,
RA   Myers J.N.;
RT   "Acquisition of anoikis resistance is a critical step in the
RT   progression of oral tongue cancer.";
RL   Oral Oncol. 39:648-655(2003).
//
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662;
RA   Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C.,
RA   Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G.,
RA   Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.;
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).
//
RX   PubMed=32574978; DOI=10.1016/j.tranon.2020.100808; PMCID=PMC7317296;
RA   Nair T.S., Thomas T.B., Yang L., Kakaraparthi B.N., Morris A.C.,
RA   Clark A.M., Campredon L.P., Brouwer A.F., Eisenberg M.C., Meza R.,
RA   Carey T.E.;
RT   "Characteristics of head and neck squamous cell carcinoma cell lines
RT   reflect human tumor biology independent of primary etiologies and HPV
RT   status.";
RL   Transl. Oncol. 13:100808.1-100808.9(2020).
//