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Cellosaurus SKOV3/MRP7 (CVCL_B3Q0)

[Text version]
Cell line name SKOV3/MRP7
Accession CVCL_B3Q0
Resource Identification Initiative To cite this cell line use: SKOV3/MRP7 (RRID:CVCL_B3Q0)
Comments Population: Caucasian.
Doubling time: 68.19 +- 1.53 hours (PubMed=34631561).
Transfected with: HGNC; 52; ABCC10.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line

PubMed=34631561; DOI=10.3389/fonc.2021.731260
Wang J.-Q., Wu Z.-X., Yang Y., Li J.-S., Yang D.-H., Fan Y.-F., Chen Z.-S.
Establishment and characterization of a novel multidrug resistant human ovarian cancer cell line with heterogenous MRP7 overexpression.
Front. Oncol. 11:731260.1-731260.10(2021)

Cell line databases/resources cancercelllines; CVCL_B3Q0
Encyclopedic resources Wikidata; Q110433238
Entry history
Entry creation16-Dec-2021
Last entry update05-Oct-2023
Version number5