ID   SKOV3/MRP7
AC   CVCL_B3Q0
DR   cancercelllines; CVCL_B3Q0
DR   Wikidata; Q110433238
RX   PubMed=34631561;
CC   Population: Caucasian.
CC   Doubling time: 68.19 +- 1.53 hours (PubMed=34631561).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 52; ABCC10.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C7978; Ovarian serous cystadenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0532 ! SK-OV-3
SX   Female
AG   64Y
CA   Cancer cell line
DT   Created: 16-12-21; Last updated: 05-10-23; Version: 5
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RX   PubMed=34631561; DOI=10.3389/fonc.2021.731260;
RA   Wang J.-Q., Wu Z.-X., Yang Y., Li J.-S., Yang D.-H., Fan Y.-F.,
RA   Chen Z.-S.;
RT   "Establishment and characterization of a novel multidrug resistant
RT   human ovarian cancer cell line with heterogenous MRP7
RT   overexpression.";
RL   Front. Oncol. 11:731260.1-731260.10(2021).
//