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Cellosaurus T21-KC-K4DT (CVCL_B3M3)

[Text version]
Cell line name T21-KC-K4DT
Accession CVCL_B3M3
Resource Identification Initiative To cite this cell line use: T21-KC-K4DT (RRID:CVCL_B3M3)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Amniotic fluid; UBERON=UBERON_0000173.
Cell type: Keratinocyte; CL=CL_0000312.
Disease Down syndrome (NCIt: C2993)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B3M2 (T21-iPSC#12)
Sex of cell Female
Age at sampling Fetus
Category Telomerase immortalized cell line
Publications

PubMed=30760866; DOI=10.1038/s41374-019-0230-0; PMCID=PMC6760570
Inoue M., Kajiwara K., Yamaguchi A., Kiyono T., Samura O., Akutsu H., Sago H., Okamoto A., Umezawa A.
Autonomous trisomic rescue of Down syndrome cells.
Lab. Invest. 99:885-897(2019)

Cross-references
Encyclopedic resources Wikidata; Q110433284
Entry history
Entry creation16-Dec-2021
Last entry update19-Dec-2024
Version number6