ID   T21-KC-K4DT
AC   CVCL_B3M3
DR   Wikidata; Q110433284
RX   PubMed=30760866;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Derived from site: In situ; Amniotic fluid; UBERON=UBERON_0000173.
CC   Cell type: Keratinocyte; CL=CL_0000312.
DI   NCIt; C2993; Down syndrome
DI   ORDO; Orphanet_870; Down syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B3M2 ! T21-iPSC#12
SX   Female
AG   Fetus
CA   Telomerase immortalized cell line
DT   Created: 16-12-21; Last updated: 19-12-24; Version: 6
//
RX   PubMed=30760866; DOI=10.1038/s41374-019-0230-0; PMCID=PMC6760570;
RA   Inoue M., Kajiwara K., Yamaguchi A., Kiyono T., Samura O., Akutsu H.,
RA   Sago H., Okamoto A., Umezawa A.;
RT   "Autonomous trisomic rescue of Down syndrome cells.";
RL   Lab. Invest. 99:885-897(2019).
//