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Cellosaurus RPE-340 (CVCL_B365)

[Text version]
Cell line name RPE-340
Synonyms RPE 340; RPE340; 340RPE
Accession CVCL_B365
Resource Identification Initiative To cite this cell line use: RPE-340 (RRID:CVCL_B365)
Comments Senescence: Senesces afer 50-60 PDL.
Caution: Indicated as originating from a 1 year old male trauma victim (PubMed=10617776) but the TERT-immortalized derived cell line hTERT-RPE1 (Cellosaurus=CVCL_4388) is stated to originate from a female donor.
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_W078 (340-RPE-11tv)CVCL_4388 (hTERT-RPE1)
Sex of cell Female
Age at sampling 1Y
Category Finite cell line

Matsunaga H., Handa J.T., Aotaki-Keen A.E., Sherwood S.W., West M.D., Hjelmeland L.M.
Beta-galactosidase histochemistry and telomere loss in senescent retinal pigment epithelial cells.
Invest. Ophthalmol. Vis. Sci. 40:197-202(1999)

Matsunaga H., Handa J.T., Gelfman C.M., Hjelmeland L.M.
The mRNA phenotype of a human RPE cell line at replicative senescence.
Mol. Vis. 5:39-39(1999)

PubMed=25177495; DOI=10.1155/2014/801787
Kuznetsova A.V., Kurinov A.M., Aleksandrova M.A.
Cell models to study regulation of cell transformation in pathologies of retinal pigment epithelium.
J. Ophthalmol. 2014:801787.1-801787.18(2014)

Encyclopedic resources Wikidata; Q54951141
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number11