Cellosaurus cell line S2/TXT (CVCL

Cellosaurus S2/TXT (CVCL_B283)

Cross-references
Cell line name	S2/TXT
Accession	CVCL_B283
Resource Identification Initiative	To cite this cell line use: S2/TXT (RRID:CVCL_B283)
Comments	Population: Japanese. Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere). Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_3172 (SUIT-2)
Sex of cell	Male
Age at sampling	73Y
Category	Cancer cell line
Publications	PubMed=11819752; DOI=10.3748/wjg.v7.i1.143; PMCID=PMC4688693 Bin Liu, Edgar Staren, Takeshi Iwamura, Hubert Appert, John Howard; Effects of taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2. World J. Gastroenterol. 7:143-148(2001) PubMed=11854916; DOI=10.3748/wjg.v7.i6.855; PMCID=PMC4695609 Bin Liu, Edgar Staren, Takeshi Iwamura, Hubert Appert, John Howard; Taxotere resistance in SUIT. Taxotere resistance in pancreatic carcinoma cell line SUIT 2 and its sublines. World J. Gastroenterol. 7:855-859(2001)
Cell line databases/resources	cancercelllines; CVCL_B283
Encyclopedic resources	Wikidata; Q54951876
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	17