ID   S2/TXT
AC   CVCL_B283
DR   cancercelllines; CVCL_B283
DR   Wikidata; Q54951876
RX   PubMed=11819752;
RX   PubMed=11854916;
CC   Population: Japanese.
CC   Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3172 ! SUIT-2
SX   Male
AG   73Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=11819752; DOI=10.3748/wjg.v7.i1.143; PMCID=PMC4688693;
RA   Liu B., Staren E., Iwamura T., Appert H., Howard J.;
RT   "Effects of taxotere on invasive potential and multidrug resistance
RT   phenotype in pancreatic carcinoma cell line SUIT-2.";
RL   World J. Gastroenterol. 7:143-148(2001).
//
RX   PubMed=11854916; DOI=10.3748/wjg.v7.i6.855; PMCID=PMC4695609;
RA   Liu B., Staren E., Iwamura T., Appert H., Howard J.;
RT   "Taxotere resistance in SUIT. Taxotere resistance in pancreatic
RT   carcinoma cell line SUIT 2 and its sublines.";
RL   World J. Gastroenterol. 7:855-859(2001).
//