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Cellosaurus PC/AA (CVCL_B261)

[Text version]
Cell line name PC/AA
Synonyms AA
Accession CVCL_B261
Resource Identification Initiative To cite this cell line use: PC/AA (RRID:CVCL_B261)
Comments Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
Disease Colorectal adenoma (NCIt: C5673)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IQ04 (PC/AA/C1)
Sex of cell Male
Age at sampling 34Y
Category Cancer cell line
Publications

PubMed=6746117; DOI=10.1002/ijc.2910340109
Christos Paraskeva, Brenda G. Buckle, Denise Sheer, Caroline B. Wigley;
The isolation and characterization of colorectal epithelial cell lines at different stages in malignant transformation from familial polyposis coli patients.
Int. J. Cancer 34:49-56(1984)

DOI=10.1007/978-1-4612-0411-4_28
Ann C. Williams, Anna M. Manning, Sara J. Harper, Christos Paraskeva;
Multiple steps in the in vitro immortalisation and neoplastic conversion of human colonic epithelial cells.
(In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim, Johng Sik & Dritschilo, Anatoly (eds.); pp.281-290; Humana Press; New York; USA (1990)

PubMed=2253215
Suzanne J. Baker, Antonette C. Preisinger, John Milburn Jessup, Christos Paraskeva, Sanford David Markowitz, James K.V. Willson, Stanley R. Hamilton, Bert Vogelstein;
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.
Cancer Res. 50:7717-7722(1990)

PubMed=2369746
Ann C. Williams, Sara J. Harper, Christos Paraskeva;
Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.
Cancer Res. 50:4724-4730(1990)

Cross-references
Encyclopedic resources Wikidata; Q54938513
Polymorphism and mutation databases IARC_TP53; 23785
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number12