| Cell line name |
PC/AA |
| Synonyms |
AA |
| Accession |
CVCL_B261 |
| Resource Identification Initiative |
To cite this cell line use: PC/AA (RRID:CVCL_B261) |
| Comments |
Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
| Sequence variations |
|
| Disease |
Colorectal adenoma (NCIt: C5673) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Children:
|
| Sex of cell |
Male |
| Age at sampling |
34Y |
| Category |
Cancer cell line |
| Publications | PubMed=6746117; DOI=10.1002/ijc.2910340109 Christos Paraskeva, Brenda G. Buckle, Denise Sheer, Caroline B. Wigley; The isolation and characterization of colorectal epithelial cell lines at different stages in malignant transformation from familial polyposis coli patients. Int. J. Cancer 34:49-56(1984) DOI=10.1007/978-1-4612-0411-4_28 Ann C. Williams, Anna M. Manning, Sara J. Harper, Christos Paraskeva; Multiple steps in the in vitro immortalisation and neoplastic conversion of human colonic epithelial cells. (In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim, Johng Sik & Dritschilo, Anatoly (eds.); pp.281-290; Humana Press; New York; USA (1990) PubMed=2253215 Suzanne J. Baker, Antonette C. Preisinger, John Milburn Jessup, Christos Paraskeva, Sanford David Markowitz, James K.V. Willson, Stanley R. Hamilton, Bert Vogelstein; p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 50:7717-7722(1990) PubMed=2369746 Ann C. Williams, Sara Jayne Harper, Christos Paraskeva; Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence. Cancer Res. 50:4724-4730(1990) |
| Cross-references |
| Encyclopedic resources |
Wikidata; Q54938513
|
| Polymorphism and mutation databases |
IARC_TP53; 23785
|
| Entry history |
| Entry creation | 06-Jun-2012 |
| Last entry update | 19-Dec-2024 |
| Version number | 12 |
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