Cellosaurus logo
expasy logo

Cellosaurus TTC-442 (CVCL_B255)

[Text version]
Cell line name TTC-442
Synonyms TTC442; TC-442; TU-442; A91
Accession CVCL_B255
Resource Identification Initiative To cite this cell line use: TTC-442 (RRID:CVCL_B255)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: MD Anderson Cell Lines Project.
Omics: Genomics; Whole exome sequencing.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Proteomics; Subcellular; Cell surface.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO11
D2S133820,21
D3S135816,18
D5S81810,11
D7S82010,13
D8S117911,14
D13S31711,12
D16S53911,14
D18S5115,24
D19S43313,16.2
D21S1129
FGA27
TH019
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

CLPUB00569
Paul S. Dickman, Maria G. Tsokos, Timothy J. Triche;
Biology of rhabdomyosarcoma: cell culture, xenografts, and animal models.
(In book chapter) Rhabdomyosarcoma and related tumors in children and adolescents; Maurer, Harold M. & Ruymann, Frederick Beeman & Pochedly, Carl Eugene (eds.); pp.49-88; CRC Press; Boca Raton; USA (1991)

PubMed=7882340
Poul H.B. Sorensen, Hiroyuki Shimada, Xian F. Liu, Jerian F. Lim, Gilles Thomas, Timothy J. Triche;
Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene.
Cancer Res. 55:1385-1392(1995)

PubMed=10602515; DOI=10.1038/sj.onc.1203168
Marc F. DeCristofaro, Bryan L. Betz, Wei-Dong Wang, Bernard E. Weissman;
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
Oncogene 18:7559-7565(1999)

PubMed=19887553; DOI=10.1158/1535-7163.MCT-09-0365; PMCID=PMC2783569
Kai-Ji Hu, Cathy Lee, De-Xin Qiu, Abbas Fotovati, Alastair Davies, Samah Abu-Ali, Daniel H. Wai, Elizabeth R. Lawlor, Timothy J. Triche, Catherine J. Pallen, Sandra E. Dunn;
Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.
Mol. Cancer Ther. 8:3024-3035(2009)

PubMed=23882450; DOI=10.3389/fonc.2013.00183; PMCID=PMC3713458
Ashley R.P. Hinson, Rosanne Jones, Lisa E.S. Crose, Brian C. Belyea, Frederic G. Barr, Corinne Mary Linardic;
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Front. Oncol. 3:183.1-183.12(2013)

PubMed=23665679; DOI=10.1038/onc.2013.129
Elizabeth I. Sokolowski, Claire B. Turina, Ken Kikuchi, David M. Langenau, Charles Keller;
Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.
Oncogene 33:1877-1889(2014)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=36768928; DOI=10.3390/ijms24032601; PMCID=PMC9917031
Andrea Timpanaro, Caroline Piccand, Anne-Christine Uldry, Peter-Karl Bode, Dzhangar Dzhumashev, Rita Sala, Manfred Heller, Jochen Rossler, Michele Bernasconi;
Surfaceome profiling of cell lines and patient-derived xenografts confirm FGFR4, NCAM1, CD276, and highlight AGRL2, JAM3, and L1CAM as surface targets for rhabdomyosarcoma.
Int. J. Mol. Sci. 24:2601.1-2601.28(2023)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01458
DepMap; ACH-001750
Encyclopedic resources Wikidata; Q54973233
Polymorphism and mutation databases Cosmic; 802050
Proteomic databases PRIDE; PXD039480
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number21