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Cellosaurus HUES 64 (CVCL_B199)

[Text version]
Cell line name HUES 64
Synonyms HUES64; HuES64
Accession CVCL_B199
Resource Identification Initiative To cite this cell line use: HUES 64 (RRID:CVCL_B199)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0067.
Registration: Swiss research registry; BAG-hES-IMP-0054.
Omics: Genomics; ChIP-seq; H3K27ac.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K36me3.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; ChIP-seq; H3K9ac.
Omics: Genomics; ChIP-seq; H3K9me3.
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Donor information: Embryo is sibling to those giving rise to HUES 62 (Cellosaurus=CVCL_B197) and HUES 63 (Cellosaurus=CVCL_B198).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX,Y
CSF1PO12
D2S133818,20
D3S135815
D5S81811,13
D7S82011,12
D8S117912,14
D16S53911,13
D19S43313,14
D21S1131,31.2
TH016,9
TPOX8,10
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Alice E. Chen, Dietrich Meinrad Egli, Kathy K. Niakan, Jie Deng, Hidenori Akutsu, Mariko Yamaki, Chad A. Cowan, Claire Fitz-Gerald, Kun Zhang, Douglas A. Melton, Kevin Carl Eggan;
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454
Christoph Bock, Evangelos Kiskinis, Griet Verstappen, Hong-Cang Gu, Gabriella L. Boulting, Zachary D. Smith, Michael Johannes Ziller, Gist Fralley Croft, Mackenzie Weygandt Amoroso, Derek H. Oakley, Andreas Gnirke ...Show all 13 authors... , Kevin Carl Eggan, Alexander Meissner; Show fewer authors
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-10-0067
SKIP; SKIP001551
Biological sample resources ENCODE; ENCBS015UPH
ENCODE; ENCBS078ITI
ENCODE; ENCBS179VGA
ENCODE; ENCBS183DGX
ENCODE; ENCBS389KQW
ENCODE; ENCBS479IFR
ENCODE; ENCBS553VXQ
ENCODE; ENCBS614QHK
ENCODE; ENCBS666HUG
ENCODE; ENCBS766XXZ
ENCODE; ENCBS918DAB
Encyclopedic resources Wikidata; Q54896803
Experimental variables resources EFO; EFO_0007089
Gene expression databases GEO; GSM621594
GEO; GSM637772
GEO; GSM669928
GEO; GSM669932
GEO; GSM669963
GEO; GSM669966
GEO; GSM669967
GEO; GSM669974
GEO; GSM772749
GEO; GSM772750
GEO; GSM772751
GEO; GSM772752
GEO; GSM772754
GEO; GSM772756
GEO; GSM772800
GEO; GSM772807
GEO; GSM772856
GEO; GSM772912
GEO; GSM772913
GEO; GSM772971
GEO; GSM772977
GEO; GSM772978
GEO; GSM772979
GEO; GSM772980
GEO; GSM773002
GEO; GSM773003
GEO; GSM997249
GEO; GSM1112775
GEO; GSM1112834
GEO; GSM1112837
GEO; GSM1112840
GEO; GSM1112841
GEO; GSM1227087
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number26