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Cellosaurus HUES 62 (CVCL_B197)

[Text version]
Cell line name HUES 62
Synonyms HUES62
Accession CVCL_B197
Resource Identification Initiative To cite this cell line use: HUES 62 (RRID:CVCL_B197)
Comments From: Harvard University; Boston; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0065.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Donor information: Embryo is sibling to those giving rise to HUES 63 (Cellosaurus=CVCL_B198) and HUES 64 (Cellosaurus=CVCL_B199).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=19200798

Markers:
AmelogeninX
CSF1PO9,12
D2S133820,22
D3S135815,20
D5S81811
D7S82010,12
D8S117913
D13S3179,12
D16S53912
D18S5115,16
D19S43313,14
D21S1129,31.2
FGA23,24
TH019,9.3
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201
Chen A.E., Egli D.M., Niakan K.K., Deng J., Akutsu H., Yamaki M., Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell 4:103-106(2009)

PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454
Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D., Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A., Eggan K.C., Meissner A.
Reference maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell 144:439-452(2011)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-10-0065
SKIP; SKIP001543
Biological sample resources ENCODE; ENCBS107ECP
CRISP screens repositories BioGRID_ORCS_Cell_line; 45
Encyclopedic resources Wikidata; Q54896801
Experimental variables resources EFO; EFO_0007087
Gene expression databases GEO; GSM621595
GEO; GSM637770
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number25