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Cellosaurus UOK121 (CVCL_B100)

[Text version]
Cell line name UOK121
Synonyms UOK-121; UOK 121; UoK121
Accession CVCL_B100
Resource Identification Initiative To cite this cell line use: UOK121 (RRID:CVCL_B100)
Comments Misspelling: Re-121; IARC_TP53=723; Note=Not really a misspelling but an assignment of a name based on first author of publication because assignment of correct cell line name was not done correctly.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys275Tyr (c.824G>A); ClinVar=VCV000215997; Zygosity=Unspecified (PubMed=8319216).
Disease Renal cell carcinoma (NCIt: C9385)
Renal cell carcinoma (ORDO: Orphanet_217071)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B101 ! UOK121LN
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=1345811
Anglard P., Trahan E.E. Jr., Liu S., Latif F., Merino M.J., Lerman M.I., Zbar B., Linehan W.M.
Molecular and cellular characterization of human renal cell carcinoma cell lines.
Cancer Res. 52:348-356(1992)

PubMed=8319216
Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.
Chromosome 17p deletions and p53 mutations in renal cell carcinoma.
Cancer Res. 53:3092-3097(1993)

PubMed=9255309; DOI=10.1016/S0090-4295(97)00220-3
Walther M.M., Kleiner D.E., Lubensky I.A., Pozzatti R., Nyguen T., Gnarra J.R., Hurley K., Venzon D., Linehan W.M., Stetler-Stevenson W.G.
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Urology 50:295-301(1997)

PubMed=12759923; DOI=10.1002/gcc.10209
Pavlovich C.P., Padilla-Nash H.M., Wangsa D., Nickerson M.L., Matrosova V., Linehan W.M., Ried T., Phillips J.L.
Patterns of aneuploidy in stage IV clear cell renal cell carcinoma revealed by comparative genomic hybridization and spectral karyotyping.
Genes Chromosomes Cancer 37:252-260(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B100
SKY/M-FISH/CGH; 1480
Encyclopedic resources Wikidata; Q54991335
Polymorphism and mutation databases IARC_TP53; 723
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number14