ID   UOK121
AC   CVCL_B100
SY   UOK-121; UOK 121; UoK121
DR   cancercelllines; CVCL_B100
DR   IARC_TP53; 723
DR   SKY/M-FISH/CGH; 1480
DR   Wikidata; Q54991335
RX   PubMed=1345811;
RX   PubMed=8319216;
RX   PubMed=9255309;
RX   PubMed=12759923;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys275Tyr (c.824G>A); ClinVar=VCV000215997; Zygosity=Unspecified (PubMed=8319216).
CC   Misspelling: Re-121; IARC_TP53=723; Note=Not really a misspelling but an assignment of a name based on first author of publication because assignment of correct cell line name was not done correctly.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C9385; Renal cell carcinoma
DI   ORDO; Orphanet_217071; Renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_B101 ! UOK121LN
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 15
//
RX   PubMed=1345811;
RA   Anglard P., Trahan E.E. Jr., Liu S., Latif F., Merino M.J., Lerman M.I.,
RA   Zbar B., Linehan W.M.;
RT   "Molecular and cellular characterization of human renal cell carcinoma
RT   cell lines.";
RL   Cancer Res. 52:348-356(1992).
//
RX   PubMed=8319216;
RA   Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.;
RT   "Chromosome 17p deletions and p53 mutations in renal cell carcinoma.";
RL   Cancer Res. 53:3092-3097(1993).
//
RX   PubMed=9255309; DOI=10.1016/S0090-4295(97)00220-3;
RA   Walther M.M., Kleiner D.E., Lubensky I.A., Pozzatti R., Nyguen T.,
RA   Gnarra J.R., Hurley K., Venzon D., Linehan W.M.,
RA   Stetler-Stevenson W.G.;
RT   "Progelatinase A mRNA expression in cell lines derived from tumors in
RT   patients with metastatic renal cell carcinoma correlates inversely
RT   with survival.";
RL   Urology 50:295-301(1997).
//
RX   PubMed=12759923; DOI=10.1002/gcc.10209;
RA   Pavlovich C.P., Padilla-Nash H.M., Wangsa D., Nickerson M.L.,
RA   Matrosova V., Linehan W.M., Ried T., Phillips J.L.;
RT   "Patterns of aneuploidy in stage IV clear cell renal cell carcinoma
RT   revealed by comparative genomic hybridization and spectral
RT   karyotyping.";
RL   Genes Chromosomes Cancer 37:252-260(2003).
//