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Cellosaurus HepG2/TC155 (CVCL_B0UI)

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Cell line name HepG2/TC155
Accession CVCL_B0UI
Resource Identification Initiative To cite this cell line use: HepG2/TC155 (RRID:CVCL_B0UI)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2013191.
Population: Caucasian.
Characteristics: Transfected with a hepatitis B virus capsid protein that contains a tetracysteine (TC) C-C-P-G-C-C insertion in position 115. The TC tag specifically reacts with a membrane-permeable biarsenical fluorescent dye (ReAsH) (PubMed=24373334).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03146; Hepatitis B virus genotype D subtype ayw capsid protein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=24373334; DOI=10.1111/liv.12419
Shu-Zhen Sun, Jing-Jun Yan, Chao Xia, Yuan-Yuan Lin, Xiao-Rui Jiang, Hao-Jing Liu, Huan-Ping Ren, Jun-Wei Yan, Ju-Sheng Lin, Xing-Xing He;
Visualizing hepatitis B virus with biarsenical labelling in living cells.
Liver Int. 34:1532-1542(2014)

Patent=CN103667194B
Ju-Sheng Lin, Jia-Zhi Liao, Shu-Zhen Sun, Jing-Jun Yan, Xing-Xing He, Ying Chang, De-An Tian, Qiu Zhao, Zi-Li Dan;
Human liver cancer cell line for observing life period of hepatitis B virus in cells and applications thereof.
Patent number CN103667194B, 30-Sep-2015

Cross-references
Cell line databases/resources cancercelllines; CVCL_B0UI
CCRID; 4201PAT-CCTCC00437
Encyclopedic resources Wikidata; Q108820460
Entry history
Entry creation23-Sep-2021
Last entry update27-Nov-2025
Version number9