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Cellosaurus HepG2.A64 (CVCL_B0UH)

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Cell line name HepG2.A64
Synonyms A64
Accession CVCL_B0UH
Resource Identification Initiative To cite this cell line use: HepG2.A64 (RRID:CVCL_B0UH)
Comments Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C201163.
Population: Caucasian.
Virology: Transfected with a plasmid pTriexHBV1.1 containing 1.1 copies of hepatitis B virus (HBV) DNA (GenBank: HQ638218.1) (PubMed=28382278).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=28382278; DOI=10.3389/fcimb.2017.00091; PMCID=PMC5360708
Hao Li, Chun-Yu Sheng, Shan Wang, Lang Yang, Yuan Liang, Yong Huang, Hong-Bo Liu, Peng Li, Chao-Jie Yang, Xiao-Xia Yang, Lei-Li Jia ...Show all 23 authors... , Jing Xie, Li-Gui Wang, Rong-Zhang Hao, Xin-Ying Du, Dong-Ping Xu, Jian-Jun Zhou, Ming-Zhen Li, Yan-Song Sun, Yi-Gang Tong, Qiao Li, Shao-Fu Qiu, Hong-Bin Song; Show fewer authors
Removal of integrated hepatitis B virus DNA using CRISPR-Cas9.
Front. Cell. Infect. Microbiol. 7:91.1-91.9(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B0UH
Encyclopedic resources Wikidata; Q108820458
Entry history
Entry creation23-Sep-2021
Last entry update10-Apr-2025
Version number8