Cellosaurus cell line RAO-3 (CVCL

Cellosaurus RAO-3 (CVCL_B0CL)

Cross-references
Cell line name	RAO-3
Accession	CVCL_B0CL
Resource Identification Initiative	To cite this cell line use: RAO-3 (RRID:CVCL_B0CL)
Comments	Characteristics: Tumorigenic. Generates human mammary spindle cell carcinomas when injected into nude mice (PubMed=16395697). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gln61Leu). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367. Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_B0CJ (RAO-1)
Sex of cell	Female
Age at sampling	Age unspecified
Category	Telomerase immortalized cell line
Publications	PubMed=16395697; DOI=10.1002/ijc.21739 Ji-Ming Cheng, Ming Ding, Ahmed Aribi, Prabodh Shah, Krishna Rao; Loss of RAB25 expression in breast cancer. Int. J. Cancer 118:2957-2964(2006) PubMed=16729884; DOI=10.1186/1475-2867-6-15; PMCID=PMC1524989 Krishna Rao, Ozge Alper, Kent E. Opheim, George Bonnet, Kristine Wolfe, Eileen Mary Bryant, Siobhan Margaret O'Hara Larivee, Peggy L. Porter, James Kinloch McDougall; Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells. Cancer Cell Int. 6:15.1-15.11(2006)
Encyclopedic resources	Wikidata; Q108821207
Experimental variables resources	EFO; EFO_0022699
Entry history
Entry creation	23-Sep-2021
Last entry update	19-Dec-2024
Version number	6