ID   RAO-3
AC   CVCL_B0CL
DR   EFO; EFO_0022699
DR   Wikidata; Q108821207
RX   PubMed=16395697;
RX   PubMed=16729884;
CC   Characteristics: Tumorigenic. Generates human mammary spindle cell carcinomas when injected into nude mice (PubMed=16395697).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gln61Leu).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
CC   Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B0CJ ! RAO-1
SX   Female
AG   Age unspecified
CA   Telomerase immortalized cell line
DT   Created: 23-09-21; Last updated: 19-12-24; Version: 6
//
RX   PubMed=16395697; DOI=10.1002/ijc.21739;
RA   Cheng J.-M., Ding M., Aribi A., Shah P., Rao K.;
RT   "Loss of RAB25 expression in breast cancer.";
RL   Int. J. Cancer 118:2957-2964(2006).
//
RX   PubMed=16729884; DOI=10.1186/1475-2867-6-15; PMCID=PMC1524989;
RA   Rao K., Alper O., Opheim K.E., Bonnet G., Wolfe K., Bryant E.M.,
RA   O'Hara Larivee S.M., Porter P.L., McDougall J.K.;
RT   "Cytogenetic characterization and H-ras associated transformation of
RT   immortalized human mammary epithelial cells.";
RL   Cancer Cell Int. 6:15.1-15.11(2006).
//