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Cellosaurus COLO 720E contaminated (CVCL_AV69)

[Text version]
Cell line name COLO 720E contaminated
Accession CVCL_AV69
Resource Identification Initiative To cite this cell line use: COLO 720E contaminated (RRID:CVCL_AV69)
Comments Problematic cell line: Contaminated. The stock of COLO 720E distributed by ECACC was contaminated by COLO 704 (PubMed=25230021; PubMed=25877200).
Part of: OCCP ovarian cancer cell line panel.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00438.
Population: Caucasian.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Ascites; Note=From a colon metastasis; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys382Asnfs*40 (c.1146delA); ClinVar=VCV001408583; Zygosity=Heterozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1994 (COLO 704)
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): PubMed=25230021; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,12
D3S135817
D5S81812,15
D7S82011,13
D8S117911,12
D13S3179,12
D16S53912,13,14
D18S5114
D21S1127,31.2
FGA20,23
Penta D10.4,12 (PubMed=25230021)
11,12 (PubMed=25877200)
Penta E11,12
TH017,9.3
TPOX8
vWA15,16

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Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=25230021; DOI=10.1371/journal.pone.0103988; PMCID=PMC4167545
Corine M. Beaufort, Jean C.A. Helmijr, Anna M. Piskorz, Marlous Hoogstraat, Kirsten Ruigrok-Ritstier, Nicolle Besselink, Muhammed Murtaza, Wilfred F.J. van IJcken, Anouk A.J. Heine, Marcel Smid, Marco J. Koudijs ...Show all 14 authors... , James D. Brenton, Els M.J.J. Berns, Jozien Helleman; Show fewer authors
Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.
PLoS ONE 9:e103988.1-e103988.16(2014)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

Cross-references
Cell line collections (Providers) ECACC; 93072111 - Discontinued
Cell line databases/resources cancercelllines; CVCL_AV69
Biological sample resources BioSample; SAMN03473075
Encyclopedic resources Wikidata; Q54814142
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM1291132
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number21