ID   COLO 720E contaminated
DR   ArrayExpress; E-MTAB-783
DR   BioSample; SAMN03473075
DR   cancercelllines; CVCL_AV69
DR   ECACC; 93072111
DR   GEO; GSM1291132
DR   Wikidata; Q54814142
RX   PubMed=25230021;
RX   PubMed=25877200;
CC   Problematic cell line: Contaminated. The stock of COLO 720E distributed by ECACC was contaminated by COLO 704 (PubMed=25230021; PubMed=25877200).
CC   Part of: OCCP ovarian cancer cell line panel.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00438.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys382Asnfs*40 (c.1146delA); ClinVar=VCV001408583; Zygosity=Heterozygous (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: ECACC; 93072111; true.
CC   Derived from site: Metastatic; Ascites; Note=From a colon metastasis; UBERON=UBERON_0007795.
ST   Source(s): PubMed=25230021; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 9,12
ST   D16S539: 12,13,14
ST   D18S51: 14
ST   D21S11: 27,31.2
ST   D3S1358: 17
ST   D5S818: 12,15
ST   D7S820: 11,13
ST   D8S1179: 11,12
ST   FGA: 20,23
ST   Penta D: 10.4,12 (PubMed=25230021)
ST   Penta D: 11,12 (PubMed=25877200)
ST   Penta E: 11,12
ST   TH01: 7,9.3
ST   TPOX: 8
ST   vWA: 15,16
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1994 ! COLO 704
SX   Female
AG   46Y
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 02-05-24; Version: 19
RX   PubMed=25230021; DOI=10.1371/journal.pone.0103988;
RA   Beaufort C.M., Helmijr J.C.A., Piskorz A.M., Hoogstraat M.,
RA   Ruigrok-Ritstier K., Besselink N., Murtaza M., van IJcken W.F.J.,
RA   Heine A.A.J., Smid M., Koudijs M.J., Brenton J.D., Berns E.M.J.J.,
RA   Helleman J.;
RT   "Ovarian cancer cell line panel (OCCP): clinical importance of in
RT   vitro morphological subtypes.";
RL   PLoS ONE 9:E103988-E103988(2014).
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).