• Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Val54fs (c.160delG); Zygosity=Homozygous (PubMed=29846633; PubMed=30737244).
  
• Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Homozygous; Note=In promoter (PubMed=29846633; PubMed=30737244).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Pro (c.845G>C); ClinVar=VCV000376659; Zygosity=Heterozygous (PubMed=29846633; PubMed=30737244).
  

CLPUB00321
Laura A. Marlow, Stephen Davis Rohl, Gregory T. Kennedy, Dragana Milosevic, Stefan K.G. Grebe, Honey V. Reddi, Norman L. Eberhardt, John C. Morris, Maria A. Trujillo, Samantha J. McDonough, Bryan McIver ...Show all 15 authors... , Keith C. Bible, John D. Casler, Robert Christian Smallridge, John Alton Copland 3rd; Show fewer authors
Newly characterized follicular thyroid carcinoma cell lines demonstrate antitumor synergy in response to combined MEK and AKT inhibitors.
(In conference) 82nd annual meeting of the American Thyroid Association; pp.A61-A61; American Thyroid Association; Quebec; Canada (2012)

PubMed=25675381; DOI=10.1210/jc.2014-2764; PMCID=PMC4422887
Christina A. von Roemeling, Laura A. Marlow, Anthony B. Pinkerton, Angela Crist, James Miller, Han W. Tun, Robert Christian Smallridge, John Alton Copland 3rd;
Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target.
J. Clin. Endocrinol. Metab. 100:E697-E709(2015)

PubMed=29846633; DOI=10.1210/jc.2017-01845; PMCID=PMC6126888
Laura A. Marlow, Stephen Davis Rohl, James L. Miller, Jeffrey A. Knauf, James Alexander Fagin, Mabel M. Ryder, Dragana Milosevic, Brian C. Netzel, Stefan K.G. Grebe, Honey V. Reddi, Robert Christian Smallridge, John Alton Copland 3rd;
Methodology, criteria, and characterization of patient-matched thyroid cell lines and patient-derived tumor xenografts.
J. Clin. Endocrinol. Metab. 103:3169-3182(2018)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953; PMCID=PMC6522280
Inigo Landa, Nikita Pozdeyev, Christopher T. Korch, Laura A. Marlow, Robert Christian Smallridge, John Alton Copland 3rd, Ying C. Henderson, Stephen Y. Lai, Gary L. Clayman, Naoyoshi Onoda, Aik-Choon Tan ...Show all 16 authors... , Maria E.R. Garcia-Rendueles, Jeffrey A. Knauf, Bryan R. Haugen, James Alexander Fagin, Rebecca E. Schweppe; Show fewer authors
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)