Cellosaurus logo
expasy logo

Cellosaurus HCEC 1CTR (CVCL_AV03)

[Text][XML][JSON]
Cell line name HCEC 1CTR
Synonyms HCEC 1CT + shTP53; 1CTR
Accession CVCL_AV03
Resource Identification Initiative To cite this cell line use: HCEC 1CTR (RRID:CVCL_AV03)
Comments Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11998; TP53.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AQ45 (HCEC 1CT)
Sex of cell Male
Age at sampling 54Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=27047802

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,14
D7S8209,11
D13S31712,13
D16S53910,11
D21S1128
TH019.3
TPOX11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794; PMCID=PMC3326261
Ugur Eskiocak, Sang Bum Kim, Peter Ly, Andres I. Roig, Sebastian Biglione, Kakajan Komurov, Crystal Cornelius, Woodring Erik Wright, Michael A. White, Jerry W. Shay;
Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth.
Cancer Res. 71:4359-4365(2011)

PubMed=27047802; DOI=10.3389/fcimb.2016.00034; PMCID=PMC4803749
Vanessa Graillot, Inge Dormoy, Jacques Dupuy, Jerry W. Shay, Laurence Huc, Gladys Mirey, Julien Vignard;
Genotoxicity of cytolethal distending toxin (CDT) on isogenic human colorectal cell lines: potential promoting effects for colorectal carcinogenesis.
Front. Cell. Infect. Microbiol. 6:34.1-34.13(2016)

Cross-references
Encyclopedic resources Wikidata; Q54881863
Entry history
Entry creation02-May-2016
Last entry update19-Dec-2024
Version number8