Cellosaurus logo
expasy logo

Cellosaurus HCEC 1CTR (CVCL_AV03)

[Text version]
Cell line name HCEC 1CTR
Synonyms HCEC 1CT + shTP53; 1CTR
Accession CVCL_AV03
Resource Identification Initiative To cite this cell line use: HCEC 1CTR (RRID:CVCL_AV03)
Comments Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11998; TP53.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AQ45 (HCEC 1CT)
Sex of cell Male
Age at sampling 54Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=27047802

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,14
D7S8209,11
D13S31712,13
D16S53910,11
D21S1128
TH019.3
TPOX11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794; PMCID=PMC3326261
Eskiocak U., Kim S.B., Ly P., Roig A.I., Biglione S., Komurov K., Cornelius C., Wright W.E., White M.A., Shay J.W.
Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth.
Cancer Res. 71:4359-4365(2011)

PubMed=27047802; DOI=10.3389/fcimb.2016.00034; PMCID=PMC4803749
Graillot V., Dormoy I., Dupuy J., Shay J.W., Huc L., Mirey G., Vignard J.
Genotoxicity of cytolethal distending toxin (CDT) on isogenic human colorectal cell lines: potential promoting effects for colorectal carcinogenesis.
Front. Cell. Infect. Microbiol. 6:34.1-34.13(2016)

Cross-references
Encyclopedic resources Wikidata; Q54881863
Entry history
Entry creation02-May-2016
Last entry update19-Dec-2024
Version number8