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Cellosaurus HCEC 1CTP (CVCL_AV02)

[Text version]
Cell line name HCEC 1CTP
Synonyms HCEC 1CT + KrasV12; 1CTP
Accession CVCL_AV02
Resource Identification Initiative To cite this cell line use: HCEC 1CTP (RRID:CVCL_AV02)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6407; KRAS (Note=With p.Gly12Val (c.35G>T)).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AQ45 (HCEC 1CT)
Sex of cell Male
Age at sampling 54Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=27047802

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,14
D7S8209,11
D13S31712,13
D16S53910,11
D21S1128
TH019.3
TPOX11
vWA16,18

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Publications

PubMed=21527559; DOI=10.1158/0008-5472.CAN-11-0794; PMCID=PMC3326261
Eskiocak U., Kim S.B., Ly P., Roig A.I., Biglione S., Komurov K., Cornelius C., Wright W.E., White M.A., Shay J.W.
Functional parsing of driver mutations in the colorectal cancer genome reveals numerous suppressors of anchorage-independent growth.
Cancer Res. 71:4359-4365(2011)

PubMed=27047802; DOI=10.3389/fcimb.2016.00034; PMCID=PMC4803749
Graillot V., Dormoy I., Dupuy J., Shay J.W., Huc L., Mirey G., Vignard J.
Genotoxicity of cytolethal distending toxin (CDT) on isogenic human colorectal cell lines: potential promoting effects for colorectal carcinogenesis.
Front. Cell. Infect. Microbiol. 6:34.1-34.13(2016)

Cross-references
Encyclopedic resources Wikidata; Q54881862
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number10