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Cellosaurus MPNST-724 (CVCL_AU20)

[Text version]
Cell line name MPNST-724
Synonyms MPNST724
Accession CVCL_AU20
Resource Identification Initiative To cite this cell line use: MPNST-724 (RRID:CVCL_AU20)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~24 hours (PubMed=21084276).
Omics: Transcriptomics; Microarray.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.280delTCA; Zygosity=Unspecified (PubMed=21084276).
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=19890883; DOI=10.1002/path.2633; PMCID=PMC4058327
Subbaya Subramanian, Venugopal Thayanithy, Robert B. West, Cheng-Han Lee, Andrew H. Beck, Shirley Zhu, Erinn Downs-Kelly, Kelli D. Montgomery, John R. Goldblum, Pancras Cornelis Wilhelmus Hogendoorn, Christopher L. Corless ...Show all 18 authors... , Andre M. Oliveira, Sarah M. Dry, Torsten O. Nielsen, Brian P. Rubin, Jonathan A. Fletcher, Christopher David Marsden Fletcher, Matt van de Rijn; Show fewer authors
Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours.
J. Pathol. 220:58-70(2010)

PubMed=21084276; DOI=10.1158/0008-5472.CAN-10-2799; PMCID=PMC3064267
Gonzalo Lopez, Keila Enitt Torres, Jeffrey Jue-Hui Liu, Belinda Hernandez, Eric D. Young, Roman Belousov, Svetlana V. Bolshakov, Alexander J.F. Lazar, John M. Slopis, Ian E. McCutcheon, David J. McConkey, Dina Chelouche Lev;
Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors.
Cancer Res. 71:185-196(2011)

PubMed=25878149; DOI=10.1158/0008-5472.CAN-15-0675
Gonzalo Lopez, Keila Enitt Torres, Jeffrey Jue-Hui Liu, Belinda Hernandez, Eric D. Young, Roman Belousov, Svetlana V. Bolshakov, Alexander J.F. Lazar, John M. Slopis, Ian E. McCutcheon, David J. McConkey, Dina Chelouche Lev;
Correction: Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors.
Cancer Res. 75:1771-1774(2015)

PubMed=32642732; DOI=10.1093/noajnl/vdz049; PMCID=PMC7317054
Alexander Pemov, Hua Li, William Presley, Margaret R. Wallace, David T. Miller;
Genetics of human malignant peripheral nerve sheath tumors.
Neurooncol. Adv. 2:i50-i61(2020)

Cross-references
Cell line databases/resources DepMap; ACH-002710
Encyclopedic resources Wikidata; Q54906510
Entry history
Entry creation02-May-2016
Last entry update10-Apr-2025
Version number10