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Cellosaurus Pre2.8 (CVCL_AS21)

[Text version]
Cell line name Pre2.8
Synonyms PrE2.8; PRE2.8
Accession CVCL_AS21
Resource Identification Initiative To cite this cell line use: Pre2.8 (RRID:CVCL_AS21)
Comments Characteristics: At the permissive temperature (33 Celsius) proliferates. At the restrictive temperature (39 Celsius) proliferation ceases and the cells undergo morphological changes consistent with the early stages of differentiation.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_LF75 ! S2.13
Sex of cell Male
Age at sampling 71Y
Category Conditionally immortalized cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX,Y
D8S117913
D18S5112,14
D21S1129,30
FGA20
TH019
vWA17

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Publications

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
John R.W. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm Gerhard Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin Francis Arlett, Lloyd R. Kelland ...Show all 16 authors... , Maureen Harrison, Arvind K. Virmani, Timothy H. Ward, Karen L. Ayres, Paul G. Debenham; Show fewer authors
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=15258184; DOI=10.1369/jhc.4A6256.2004
Tahirah N. Alam, Michael J. O'Hare, Istvan Laczko, Alex Freeman, Farah Al-Beidh, John R.W. Masters, David L. Hudson;
Differential expression of CD44 during human prostate epithelial cell differentiation.
J. Histochem. Cytochem. 52:1083-1090(2004)

PubMed=17244020; DOI=10.1111/j.1432-0436.2006.00113.x
Bernadette Daly-Burns, Tahirah N. Alam, Alan Mackay, Jeremy Clark, Christopher J. Shepherd, Sian Rizzo, Roger Tatoud, Michael J. O'Hare, John R.W. Masters, David L. Hudson;
A conditionally immortalized cell line model for the study of human prostatic epithelial cell differentiation.
Differentiation 75:35-48(2007)

Cross-references
Encyclopedic resources Wikidata; Q54948342
Entry history
Entry creation02-May-2016
Last entry update10-Sep-2024
Version number10