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Cellosaurus Pre2.8 (CVCL_AS21)

[Text version]
Cell line name Pre2.8
Synonyms PrE2.8; PRE2.8
Accession CVCL_AS21
Resource Identification Initiative To cite this cell line use: Pre2.8 (RRID:CVCL_AS21)
Comments Characteristics: At the permissive temperature (33 Celsius) proliferates. At the restrictive temperature (39 Celsius) proliferation ceases and the cells undergo morphological changes consistent with the early stages of differentiation.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_LF75 ! S2.13
Sex of cell Male
Age at sampling 71Y
Category Conditionally immortalized cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX,Y
D8S117913
D18S5112,14
D21S1129,30
FGA20
TH019
vWA17

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Publications

PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459
Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G., Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R., Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Short tandem repeat profiling provides an international reference standard for human cell lines.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001)

PubMed=15258184; DOI=10.1369/jhc.4A6256.2004
Alam T.N., O'Hare M.J., Laczko I., Freeman A., Al-Beidh F., Masters J.R.W., Hudson D.L.
Differential expression of CD44 during human prostate epithelial cell differentiation.
J. Histochem. Cytochem. 52:1083-1090(2004)

PubMed=17244020; DOI=10.1111/j.1432-0436.2006.00113.x
Daly-Burns B., Alam T.N., Mackay A., Clark J., Shepherd C.J., Rizzo S., Tatoud R., O'Hare M.J., Masters J.R.W., Hudson D.L.
A conditionally immortalized cell line model for the study of human prostatic epithelial cell differentiation.
Differentiation 75:35-48(2007)

Cross-references
Encyclopedic resources Wikidata; Q54948342
Entry history
Entry creation02-May-2016
Last entry update10-Sep-2024
Version number10