ID   Pre2.8
AC   CVCL_AS21
SY   PrE2.8; PRE2.8
DR   Wikidata; Q54948342
RX   PubMed=11416159;
RX   PubMed=15258184;
RX   PubMed=17244020;
CC   Characteristics: At the permissive temperature (33 Celsius) proliferates. At the restrictive temperature (39 Celsius) proliferation ceases and the cells undergo morphological changes consistent with the early stages of differentiation.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
ST   Source(s): PubMed=11416159
ST   Amelogenin: X,Y
ST   D18S51: 12,14
ST   D21S11: 29,30
ST   D8S1179: 13
ST   FGA: 20
ST   TH01: 9
ST   vWA: 17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_LF75 ! S2.13
SX   Male
AG   71Y
CA   Conditionally immortalized cell line
DT   Created: 02-05-16; Last updated: 10-09-24; Version: 10
//
RX   PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459;
RA   Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G.,
RA   Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R.,
RA   Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.;
RT   "Short tandem repeat profiling provides an international reference
RT   standard for human cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
//
RX   PubMed=15258184; DOI=10.1369/jhc.4A6256.2004;
RA   Alam T.N., O'Hare M.J., Laczko I., Freeman A., Al-Beidh F.,
RA   Masters J.R.W., Hudson D.L.;
RT   "Differential expression of CD44 during human prostate epithelial cell
RT   differentiation.";
RL   J. Histochem. Cytochem. 52:1083-1090(2004).
//
RX   PubMed=17244020; DOI=10.1111/j.1432-0436.2006.00113.x;
RA   Daly-Burns B., Alam T.N., Mackay A., Clark J., Shepherd C.J.,
RA   Rizzo S., Tatoud R., O'Hare M.J., Masters J.R.W., Hudson D.L.;
RT   "A conditionally immortalized cell line model for the study of human
RT   prostatic epithelial cell differentiation.";
RL   Differentiation 75:35-48(2007).
//