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Cellosaurus MCF-7/S9 (CVCL_AS09)

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Cell line name MCF-7/S9
Synonyms MCF7/S9; MCF-7 subline 9
Accession CVCL_AS09
Resource Identification Initiative To cite this cell line use: MCF-7/S9 (RRID:CVCL_AS09)
Comments Group: Serum/protein free medium cell line.
Population: Caucasian.
Doubling time: ~44 hours, 34 hours (Note=When estradiol added in medium) (PubMed=12732292).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=3513694
Per Briand, Anne E. Lykkesfeldt;
Long-term cultivation of a human breast cancer cell line, MCF-7, in a chemically defined medium. Effect of estradiol.
Anticancer Res. 6:85-90(1986)

PubMed=12732292; DOI=10.1016/S0960-0760(03)00068-2
Janne Jensen, Jason W. Kitlen, Per Briand, Fernand Labrie, Anne E. Lykkesfeldt;
Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium.
J. Steroid Biochem. Mol. Biol. 84:469-478(2003)

Cross-references
Cell line collections (Providers) CancerTools; 152602
ECACC; 16022530 - Discontinued
Ximbio; 152602
Cell line databases/resources cancercelllines; CVCL_AS09
Encyclopedic resources Wikidata; Q54904380
Entry history
Entry creation02-May-2016
Last entry update19-Dec-2024
Version number17